Scott J. Lusher

Janssen (Belgium) — Belgium

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index17.3kcitations24works0.02yr avg
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Research Topics

Estrogen and related hormone effects(9), Computational Drug Discovery Methods(6), Research Data Management Practices(5), Scientific Computing and Data Management(4), Genetics, Bioinformatics, and Biomedical Research(4)

Publications24 total

The Need of Industry to Go FAIR
Data Intelligence·2019· 29 citedOpen Access
Addendum: The FAIR Guiding Principles for scientific data management and stewardship
Scientific Data·2019· 250 citedOpen Access
3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine
Journal of Chemical Information and Modeling·2017· 26 citedOpen Access
The FAIR Guiding Principles for scientific data management and stewardship
Scientific Data·2016· 16.6k citedOpen Access
Die FAIR-Prinzipien für das wissenschaftliche Datenmanagement und Data Stewardship
Zenodo (CERN European Organization for Nuclear Research)·2016Open Access
3-D-Echem Vm: Cheminformatics Research Infrastructure In A Downloadable Virtual Machine
Zenodo (CERN European Organization for Nuclear Research)·2016Open Access
Research Software at the Heart of Discovery: Principles of Academic Software Sustainability
Data Archiving and Networked Services (DANS)·2016Open Access
Finding the Right Approach to Big Data-Driven Medicinal Chemistry
Future Medicinal Chemistry·2015· 7 citedOpen Access
Data and compute intensive escience approaches in computational medicinal chemistry
2014
Data-driven food research—The 4th paradigm applied to nutrition
PharmaNutrition·2014
An interactive, multi-touch videowall for scientific data exploration
EGU General Assembly Conference Abstracts·2014
All scientific disciplines, including medicinal chemistry, are the subject of a revolution as data are generated at unprecedented rates and their analysis and exploitation become increasingly fundamental to innovation. Data-driven medicinal chemistry in the era of big data
2014· 1 cited
Data-driven medicinal chemistry in the era of big data
Drug Discovery Today·2013· 152 cited
Variable Loss of Functional Activities of Androgen Receptor Mutants in Patients with Androgen Insensitivity Syndrome
Sexual Development·2013· 9 citedOpen Access
Molecular determinants of partial agonism by progesterone receptor modulators : implications for drug design & discovery
2013
Org 214007-0: A Novel Non-Steroidal Selective Glucocorticoid Receptor Modulator with Full Anti-Inflammatory Properties and Improved Therapeutic Index
PLoS ONE·2012· 35 citedOpen Access
X-ray Structures of Progesterone Receptor Ligand Binding Domain in Its Agonist State Reveal Differing Mechanisms for Mixed Profiles of 11β-Substituted Steroids
Journal of Biological Chemistry·2012· 35 citedOpen Access
PR X-Ray structures in agonist conformations reveal two different mechanisms for partial agonism in 11beta-substituted steroids
2011
Structural Basis for Agonism and Antagonism for a Set of Chemically Related Progesterone Receptor Modulators
Journal of Biological Chemistry·2011· 40 citedOpen Access
A molecular informatics view on best practice in multi-parameter compound optimization
Drug Discovery Today·2011· 21 cited
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Frequent Co-authors

Ross McGuire(8), Jacob de Vlieg(7), Arie Baak(4), Jan‐Willem Boiten(4), Albert Mons(4), Rolien Bosch(4), Mark D. Wilkinson(3), Michel Dumontier(3), IJsbrand Jan Aalbersberg(3), Gabrielle Appleton(3), Myles Axton(3), Niklas Blomberg(3), Luiz Olavo Bonino da Silva Santos(3), Philip E. Bourne(3), Jildau Bouwman(3), Anthony J. Brookes(3), Ingrid Dillo(3), Olivier Dumon(3), Scott Edmunds(3), Chris T. Evelo(3)