Jonathan C. Schisler

University of North Carolina at Chapel Hill — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

40h-index4.8kcitations217works5.42yr avg
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Research Topics

Mitochondrial Function and Pathology(29), Ubiquitin and proteasome pathways(21), Metabolism, Diabetes, and Cancer(16), Spaceflight effects on biology(16), Adipose Tissue and Metabolism(15)

Publications215 total

Synergistic MAPT mutations as a platform to uncover modifiers of tau pathogenesis
2025Open Access
Synergistic MAPT mutations as a platform to uncover modifiers of tau pathogenesis
2025Open Access
Author response: Synergistic MAPT mutations as a platform to uncover modifiers of tau pathogenesis
2025Open Access
Domain-specific decoupling of co-chaperone and ligase functions in <i>STUB1</i> underlies biochemical and clinical heterogeneity in SCA48
2025Open Access
The MEK inhibitor trametinib incurs mitochondrial injury and induces innate immune responses in the mouse heart
2025Open Access
Abstract Thu120: Guardians of the Artery: Long-Term CXCL5 Infusion as a Galactic Defense Against Atheroprogression
Circulation Research·2025
Author Correction: Anisomycin prevents OGD-induced necroptosis by regulating the E3 ligase CHIP
UNC Libraries·2025Open Access
Regulation of the NaCl cotransporter NCC and blood pressure by the ubiquitin E3 ligase CHIP
Physiology·2025
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
UNC Libraries·2025Open Access
Phosphorylation-State Modulated Binding of HSP70: Structural Insights and Compensatory Protein Engineering
2025Open Access
Synergistic MAPT mutations as a platform to uncover modifiers of tau pathogenesis
2025Open Access
E3 ubiquitin ligase CHIP facilitates cAMP and cGMP signalling cross-talk by polyubiquitinating PDE9A
The EMBO Journal·2025· 3 citedOpen Access
Guardians of the Mitochondria: Space Mitochondria 2.0 Systemic Analysis Reveals Bioenergetic Dysregulation Across Species
SSRN Electronic Journal·2025· 1 citedOpen Access
Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes.
UNC Libraries·2024Open Access
Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes
Proceedings of the National Academy of Sciences·2024· 13 citedOpen Access
Aging and putative frailty biomarkers are altered by spaceflight
UNC Libraries·2024Open Access
Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology
UNC Libraries·2024Open Access
Targeting chaperone modifications: Innovative approaches to cancer treatment
UNC Libraries·2024Open Access
Targeting chaperone modifications: Innovative approaches to cancer treatment
Journal of Biological Chemistry·2024· 2 citedOpen Access
Mucus polymer concentration and in vivo adaptation converge to define the antibiotic response of Pseudomonas aeruginosa during chronic lung infection
UNC Libraries·2024Open Access
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Frequent Co-authors

Cam Patterson(21), Monte S. Willis(15), Christopher B. Newgard(10), Christopher E. Mason(8), Afshin Beheshti(8), Cem Meydan(7), Jonathan Foox(6), Deanne Taylor(6), Amanda Saravia-Butler(6), Eve Syrkin Wurtele(6), Douglas C. Wallace(5), Robert Meller(5), Victoria Zaksas(5), Rebekah Sanchez‐Hodge(5), Hossein Fazelinia(4), Larry N. Singh(4), J. Tyson McDonald(4), Sylvain V. Costes(4), Joseph W. Guarnieri(4), Christopher Mozsary(4)