Jarek Juraszek

Johnson & Johnson (Israel) — Israel

Medicine · Health Sciences

24h-index2.4kcitations59works7.22yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(14), Influenza Virus Research Studies(12), Protein Structure and Dynamics(11), Respiratory viral infections research(11), Monoclonal and Polyclonal Antibodies Research(10)

Publications55 total

VHH antibody loop guides design of a synthetic macrocyclic peptide that potently blocks influenza virus membrane fusion
npj Viruses·2025Open Access
New class of dual agonistic T-cell engagers for the in-patient activation and expansion of v delta 1 T cells with broad antigen agnostic antitumour activity
Blood·2025
1166 Avidity engineered multifunctional antibodies that strongly activate and expand anti-tumor immunity in situ, turning cold patient tumor tissue hot and exerting durable tumor control in mice
Regular and Young Investigator Award Abstracts·2025Open Access
De novo design of D-peptide ligands: Application to influenza virus hemagglutinin
Proceedings of the National Academy of Sciences·2025· 4 citedOpen Access
Abstract 4876: Avidity engineered multispecific antibodies that are highly efficacious in immune cell stimulation in patient tissue and in mice: significantly improved tumor control and turning cold tumors hot
Cancer Research·2025
A foldon-free prefusion F trimer vaccine for respiratory syncytial virus to reduce off-target immune responses
Nature Microbiology·2024· 15 citedOpen Access
Engineering a cleaved, prefusion-stabilized influenza B virus hemagglutinin by identification and locking of all six pH switches
PNAS Nexus·2024· 2 citedOpen Access
Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer
Nature Communications·2024· 27 citedOpen Access
Universal paramyxovirus vaccine design by stabilizing regions involved in structural transformation of the fusion protein
Nature Communications·2024· 10 citedOpen Access
Impact of SARS-CoV-2 spike stability and RBD exposure on antigenicity and immunogenicity
Scientific Reports·2024· 15 citedOpen Access
Absolute quantitation of binding antibodies from clinical samples
npj Vaccines·2024· 13 citedOpen Access
Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike
PLoS Pathogens·2023· 10 citedOpen Access
Booster vaccination with Ad26.COV2.S or an Omicron-adapted vaccine in pre-immune hamsters protects against Omicron BA.2
npj Vaccines·2023· 5 citedOpen Access
Efficacy, safety, and immunogenicity of a booster regimen of Ad26.COV2.S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial
The Lancet Infectious Diseases·2022· 84 citedOpen Access
Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike
2022· 1 citedOpen Access
Immunogenicity of an Ad26-based SARS-CoV-2 Omicron Vaccine in Naïve Mice and SARS-CoV-2 Spike Pre-immune Hamsters
2022· 2 citedOpen Access
Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions
Proceedings of the National Academy of Sciences·2022· 48 citedOpen Access
Ad26.COV2.S elicited neutralizing activity against Delta and other SARS-CoV-2 variants of concern
2021· 49 citedOpen Access
Stabilizing the closed SARS-CoV-2 spike trimer
Nature Communications·2021· 172 citedOpen Access
Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains
Cell Reports·2020· 44 citedOpen Access
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Frequent Co-authors

Johannes P. M. Langedijk(15), Lucy Rutten(11), Peter G. Bolhuis(10), Boerries Brandenburg(10), Robert H. Friesen(9), Sven Blokland(9), Mark J. G. Bakkers(9), Ronald Vogels(8), Jaap Goudsmit(8), Wouter Koudstaal(7), Ian A. Wilson(6), Chan Tang(6), Roland Zahn(6), Mandy Jongeneelen(5), Richard Voorzaat(5), Francesco Luigi Gervasio(5), Hanneke Schuitemaker(5), Xiaodi Yu(5), Esther J. M. Stoop(4), Wenli Yu(4)