Anna Maria Anastasi

Alfasigma (Italy) — Italy

Medicine · Health Sciences

13h-index510citations36works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(21), Radiopharmaceutical Chemistry and Applications(10), CAR-T cell therapy research(6), SARS-CoV-2 and COVID-19 Research(5), HER2/EGFR in Cancer Research(5)

Publications36 total

Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery
Molecular Therapy·2022· 2 citedOpen Access
Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery
2022Open Access
Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy
Molecular Therapy·2022Open Access
Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy
BOA (University of Milano-Bicocca)·2022· 23 cited
Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy
2021· 1 citedOpen Access
Antibody drug conjugates with hydroxamic acid cargos for histone deacetylase (HDAC) inhibition
Chemical Communications·2021· 13 citedOpen Access
ErbB2 Targeted Epigenetic Modulation: Anti-tumor Efficacy of the ADC Trastuzumab-HDACi ST8176AA1
Frontiers in Oncology·2020· 18 citedOpen Access
Synthesis and preliminary in vitro evaluation of DOTA-Tenatumomab conjugates for theranostic applications in tenascin expressing tumors
Bioorganic & Medicinal Chemistry·2019· 10 citedOpen Access
Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation
Chemical Science·2018· 33 citedOpen Access
AvidinOX-anchored biotinylated trastuzumab and pertuzumab induce down-modulation of ErbB2 and tumor cell death at concentrations order of magnitude lower than not-anchored antibodies
Oncotarget·2017· 8 citedOpen Access
Intra-tumor AvidinOX allows efficacy of low dose systemic biotinylated Cetuximab in a model of head and neck cancer
Oncotarget·2015· 6 citedOpen Access
Efficacy of aerosol therapy of lung cancer correlates with EGFR paralysis induced by AvidinOX-anchored biotinylated Cetuximab
Oncotarget·2014· 11 citedOpen Access
Optimized selection of anti-tumor recombinant antibodies from phage libraries on intact cells
Molecular Immunology·2013· 15 cited
Chemical Linkage to Injected Tissues Is a Distinctive Property of Oxidized Avidin
PLoS ONE·2011· 10 citedOpen Access
Preclinical Pharmacology and Safety of a Novel Avidin Derivative for Tissue‐Targeted Delivery of Radiolabelled Biotin
Basic & Clinical Pharmacology & Toxicology·2011· 11 citedOpen Access
Therapeutic Use of Avidin Is Not Hampered by Antiavidin Antibodies in Humans
Cancer Biotherapy and Radiopharmaceuticals·2010· 46 cited
Cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy for synchronous or metachronous peritoneal carcinomatosis from ovarian cancer
European Journal of Surgical Oncology·2010
Biochemical and Biological Characterization of a New Oxidized Avidin with Enhanced Tissue Binding Properties
Journal of Biological Chemistry·2010· 29 citedOpen Access
Oxadivin reacts with tissues and efficiently uptakes biotinylated therapeutics
New Biotechnology·2009Open Access
Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cells
BMC Biotechnology·2007· 76 citedOpen Access
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Frequent Co-authors

Rita De Santis(28), Antonio Rosi(17), Fiorella Petronzelli(14), Ferdinando Maria Milazzo(12), Claudio Albertoni(10), Caterina Chiapparino(10), Olga Minenkova(9), Gianfranco Battistuzzi(9), Daniela Santapaola(8), Angela Pelliccia(8), Valeria D’Alessio(8), Barbara Leoni(8), Laura Salvini(7), Emanuele Marra(7), Giovanni Paganelli(6), Antonio Verdoliva(6), Laura Luberto(6), Anna Riccio(5), Emilio Merlo Pich(5), Ragnar Lindstedt(4)