Susana de la Luna

Institució Catalana de Recerca i Estudis Avançats — Spain

Medicine · Health Sciences

45h-index4.8kcitations82works0.82yr avg
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Research Topics

Down syndrome and intellectual disability research(17), Influenza Virus Research Studies(15), RNA and protein synthesis mechanisms(13), Ubiquitin and proteasome pathways(13), Virus-based gene therapy research(12)

Publications82 total

DYRK1A regulates cancer cell and cancer-associated fibroblast secretomes to foster an immunosuppressive microenvironment in pancreatic cancer
2025
A novel feedback loop between DYRK2 and USP28 regulates cancer homeostasis and DNA damage signaling
Cell Death and Differentiation·2025· 2 citedOpen Access
Abstract Th0053: A Loss of Function Polymorphism in the Propeptide of Lysyl Oxidase Exacerbates Atherosclerosis
Arteriosclerosis Thrombosis and Vascular Biology·2025
The dual-specificity kinase DYRK1A interacts with the Hepatitis B virus genome and regulates the production of viral RNA
PLoS ONE·2024· 2 citedOpen Access
THE DUAL-SPECIFICITY KINASE DYRK1A INTERACTS WITH THE HEPATITIS B VIRUS GENOME AND REGULATES THE PRODUCTION OF VIRAL RNA
2024Open Access
Loss of the DYRK1A Protein Kinase Results in the Reduction in Ribosomal Protein Gene Expression, Ribosome Mass and Reduced Translation
Biomolecules·2023· 8 citedOpen Access
Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels
EBioMedicine·2023· 23 citedOpen Access
FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2
Cell Death and Disease·2023· 25 citedOpen Access
TFIIIC as a Potential Epigenetic Modulator of Histone Acetylation in Human Stem Cells
International Journal of Molecular Sciences·2023· 7 citedOpen Access
An RNA Polymerase III General Transcription Factor Engages in Cell Type-Specific Chromatin Looping
International Journal of Molecular Sciences·2022· 7 citedOpen Access
A novel CDC25A/DYRK2 regulatory switch modulates cell cycle and survival
Cell Death and Differentiation·2021· 63 citedOpen Access
Loss of the DYRK1A protein kinase results in reduction of ribosomal protein genes expression, ribosome mass and translation defects
2021Open Access
The DYRK Family of Kinases in Cancer: Molecular Functions and Therapeutic Opportunities
Cancers·2020· 88 citedOpen Access
TFIIIC Binding to Alu Elements Controls Gene Expression via Chromatin Looping and Histone Acetylation
Molecular Cell·2019· 120 citedOpen Access
A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response
Scientific Reports·2019· 42 citedOpen Access
Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome
Neurobiology of Disease·2019· 44 citedOpen Access
DYRK1A modulates c-MET in pancreatic ductal adenocarcinoma to drive tumour growth
Gut·2018· 88 cited
Impaired development of neocortical circuits contributes to the neurological alterations in <i>DYRK1A</i> haploinsufficiency syndrome
2018· 1 citedOpen Access
DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells
Cell Reports·2018· 51 citedOpen Access
DYRK1A overexpression in pancreatic ductal adenocarcinoma contributes to tumor growth
Pancreatology·2015· 1 cited
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Frequent Co-authors

Juan Ortı́n(14), Xavier Estivill(10), Amelia Nieto(8), María L. Arbonés(7), Sergi Aranda(5), Chiara Di Vona(5), Agustı́n Portela(5), Cristina Fillat(5), Ariadna Laguna(4), Mónica Álvarez‐Fernández(4), Krisztina Arató(4), Mercè Pérez‐Riba(3), Eulàlia Salichs(3), Xavier Altafaj(3), Marı́a José Barallobre(3), Juan Bárcena(3), Carles Pucharcós(3), Juan José Sanz‐Ezquerro(3), Melanie Pritchard(2), Juan Miguel Redondo(2)