Aruna Asipu

University of Leeds — United Kingdom

Medicine · Health Sciences

15h-index3.0kcitations23works0.02yr avg
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Research Topics

Diet, Metabolism, and Disease(11), Liver Disease Diagnosis and Treatment(7), Metabolism, Diabetes, and Cancer(5), Diet and metabolism studies(5), Pancreatic function and diabetes(4)

Publications23 total

Abstract 18170: Role of Ketohexokinase in Fructose-Mediated Insulin Resistance and Endothelial Dysfunction
Circulation·2017
A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development
PLoS ONE·2017· 34 citedOpen Access
P24 Sucrose- and high fat-induced insulin resistance leads to endothelial dysfunction and is associated with ketohexokinase activation
2016· 1 citedOpen Access
TRPM2-mediated intracellular Zn2+ release triggers pancreatic β-cell death
Biochemical Journal·2015· 49 citedOpen Access
Endogenous Fructose Production and Fructokinase Activation Mediate Renal Injury in Diabetic Nephropathy
Journal of the American Society of Nephrology·2014· 160 citedOpen Access
Correction: Corrigendum: Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome
Nature Communications·2013· 797 citedOpen Access
Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome
Nature Communications·2013· 235 citedOpen Access
High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase
Hepatology·2013· 311 citedOpen Access
Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice
Proceedings of the National Academy of Sciences·2012· 284 citedOpen Access
Both isoforms of ketohexokinase are dispensable for normal growth and development
Physiological Genomics·2010· 51 cited
Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response
Nature Genetics·2009· 680 citedOpen Access
Ketohexokinase: Expression and Localization of the Principal Fructose-metabolizing Enzyme
Journal of Histochemistry & Cytochemistry·2009· 186 citedOpen Access
Structures of alternatively spliced isoforms of human ketohexokinase
Acta Crystallographica Section D Biological Crystallography·2009· 44 citedOpen Access
Crystal structures of alternatively-spliced isoforms of human ketohexokinase
2007
Increased ATP-sensitive K+ channel expression during acute glucose deprivation
Biochemical and Biophysical Research Communications·2006· 21 cited
Increased expression of AMPA receptor subunits in the nucleus of the solitary tract in the spontaneously hypertensive rat
Molecular Brain Research·2004· 20 cited
Properties of Normal and Mutant Recombinant Human Ketohexokinases and Implications for the Pathogenesis of Essential Fructosuria
Diabetes·2003· 102 citedOpen Access
The Specificity of the Myelin Basic Protein Gene Promoter Studied in Transgenic Mice
Biochemical and Biophysical Research Communications·2001· 8 cited
Cell-type specific factors bind to regulatory elements located downstream of the TATA-box element in the mouse myelin basic protein (MBP) gene promoter
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression·1998· 2 cited
Stable and temperature-sensitive transformation of baby rat kidney cells by SV40 suppresses expression of membrane dipeptidase
Oncogene·1997· 10 cited
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Frequent Co-authors

David T. Bonthron(14), Christine P. Diggle(8), G. Eric Blair(6), Miguel A. Lanaspa(5), Takuji Ishimoto(5), Christopher J. Rivard(5), Carlos A. Roncal-Jiménez(5), Tomoki Kosugi(5), Laura Gabriela Sánchez‐Lozada(5), Yuri Y. Sautin(5), Richard J. Johnson(5), Christina Cicerchi(4), David J. Orlicky(4), Shinichiro Inaba(4), Shoichi Maruyama(4), Ian Carr(4), Bruce E. Hayward(4), Nanxing Li(3), J. Mark Petrash(3), Philip A. Ruzycki(2)