Christopher M. Loughrey

University of Glasgow — United Kingdom

Medicine · Health Sciences

23h-index2.0kcitations89works2.12yr avg
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Research Topics

Cardiac electrophysiology and arrhythmias(34), Ion channel regulation and function(22), Cardiac Fibrosis and Remodeling(15), Signaling Pathways in Disease(15), Neuroscience and Neural Engineering(8)

Publications88 total

Abstract 4358298: Atrial Hypertrophy, Fibrosis and Compliance Loss in a Mouse Model of Heart Failure with Preserved Ejection Fraction
Circulation·2025
Biomechanical and compositional basement membrane defects due to a Col4a1 mutation affect cardiac morphology and function
Matrix Biology·2025· 2 citedOpen Access
Abstract Fri029: Cardiomyocyte-Specific Deficiency of Core-binding Factor β Reduces Cardiac and Systemic Inflammation after Myocardial Infarction.
Circulation Research·2025
Pharmacological study of the safety, efficacy, and potential of M201-A on paroxysmal and persistent atrial fibrillation
Journal of Pharmacology and Experimental Therapeutics·2025· 2 citedOpen Access
The Heart Has Intrinsic Ketogenic Capacity that Mediates NAD <sup>+</sup> Therapy in HFpEF
Circulation Research·2025· 11 citedOpen Access
Targeting <i>Runx</i> 1 protects against heart failure with preserved ejection fraction
2025Open Access
Optimized protocols for commonly-used murine models of heart failure with preserved ejection fraction
2025Open Access
The role of IL15 in angiotensin II-mediated cardiac remodelling
European Heart Journal·2024Open Access
A novel ryanodine receptor 2 inhibitor, M201‐A, enhances natriuresis, renal function and lusi‐inotropic actions: Preclinical and phase I study
British Journal of Pharmacology·2024· 4 citedOpen Access
Ribonucleicacid interference or small molecule inhibition of<i>Runx</i>1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction
Cardiovascular Research·2023· 12 citedOpen Access
Cathepsin-K inhibition improves cardiac function post-Ischemia reperfusion injury
Journal of Molecular and Cellular Cardiology·2022
Targeting Runx1 prevents mitochondrial damage in the border zone and preserves cardiac contractility after myocardial infarction
Journal of Molecular and Cellular Cardiology·2022
Runx1 deficiency protects against heart failure with preserved ejection fraction
Journal of Molecular and Cellular Cardiology·2022
Inhibiting Runx1 protects heart function after myocardial infarction
2022· 3 cited
Preclinical models of myocardial infarction: from mechanism to translation
British Journal of Pharmacology·2021· 59 citedOpen Access
Inhibition of myocardial cathepsin-L release during reperfusion following myocardial infarction improves cardiac function and reduces infarct size
Cardiovascular Research·2021· 15 citedOpen Access
Signalling pathways linking cysteine cathepsins to adverse cardiac remodelling
Cellular Signalling·2020· 13 citedOpen Access
Abstract 339: Runx1 Knock-down by Adeno Associated Viral Mediated-delivery of Short Hairpin RNA Preserves Cardiac Contractility Following Myocardial Infarction
Circulation Research·2020
Displacement Encoding With Stimulated Echoes Enables the Identification of Infarct Transmurality Early Postmyocardial Infarction
Journal of Magnetic Resonance Imaging·2020· 3 citedOpen Access
RUNX1: an emerging therapeutic target for cardiovascular disease
Cardiovascular Research·2020· 94 citedOpen Access
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Frequent Co-authors

Godfrey L. Smith(22), Stuart A. Nicklin(10), Elspeth B. Elliott(10), Charlotte S. McCarroll(7), Tamara P. Martin(7), Katrin Nather(6), Alexandra Riddell(6), Tim Seidler(6), Noboru Kaneko(6), Weihong He(5), Thomas Braun(5), Ryuko Matsuda(5), Ian Young(4), Caroline Fattah(4), Liam J. Morrison(4), Martin McBride(4), Ewan R. Cameron(4), Gerd Hasenfuß(4), Eilidh MacDonald(4), K.E. MacEachern(4)