Constandina Pospori

The Francis Crick Institute — United Kingdom

Medicine · Health Sciences

12h-index875citations31works6.92yr avg
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Research Topics

CAR-T cell therapy research(11), Immune Cell Function and Interaction(7), Acute Myeloid Leukemia Research(5), Hematopoietic Stem Cell Transplantation(5), Immunotherapy and Immune Responses(5)

Publications31 total

Cancer-driven neutrophil priming couples systemic epithelial regenerative programs with pre-metastatic niche formation
2026Open Access
B-lineage acute lymphoblastic leukaemia disrupts a LepR+ bone marrow stromal niche which is critical for CAR-T cell persistence
Blood·2025Open Access
Optimizing scheduling in dual-pulse nucleoside labeling experiments for cell cycle analysis
2025Open Access
Clonal memory of cell division in humans diverges between healthy haematopoiesis and acute myeloid leukaemia
2025Open Access
Tumor-Infiltrating Clonal Hematopoiesis
New England Journal of Medicine·2025· 48 citedOpen Access
A subset of Haematopoietic Stem Cells resists <i>Plasmodium</i> infection-induced stress by uncoupling interferon sensing and metabolic activation
2025Open Access
SIRPα+ PD-L1+ bone marrow macrophages aid AML growth by modulating T cell function
2024Open Access
Heterogeneous run-and-tumble motion accounts for transient non-Gaussian super-diffusion in haematopoietic multi-potent progenitor cells
PLoS ONE·2022· 10 citedOpen Access
Reversible CD8 T cell–neuron cross-talk causes aging-dependent neuronal regenerative decline
Science·2022· 105 citedOpen Access
Metalloproteinase inhibition reduces AML growth, prevents stem cell loss, and improves chemotherapy effectiveness
Blood Advances·2022· 23 citedOpen Access
Heterogeneous run-and-tumble motion accounts for transient non-Gaussian super-diffusion in haematopoietic multi-potent progenitor cells
2021Open Access
Dynamic regulation of hierarchical heterogeneity in Acute Myeloid Leukemia serves as a tumor immunoevasion mechanism
2020· 1 citedOpen Access
Manipulating niche composition limits damage to haematopoietic stem cells during Plasmodium infection
Nature Cell Biology·2020· 45 citedOpen Access
GO analysis of biological processes enriched in control and infected mice
Apollo (University of Cambridge)·2020Open Access
3122 – DYNAMIC REGULATION OF HIERARCHICAL HETEROGENEITY IN ACUTE MYELOID LEUKAEMIA, SERVES AS A TUMOUR IMMUNOEVASION MECHANISM.
Experimental Hematology·2020
Author Correction: Dynamic responses of the haematopoietic stem cell niche to diverse stresses
Nature Cell Biology·2020· 3 citedOpen Access
Dynamic responses of the haematopoietic stem cell niche to diverse stresses
Nature Cell Biology·2020· 134 cited
Activated stromal cells transfer mitochondria to rescue acute lymphoblastic leukemia cells from oxidative stress
Blood·2019· 231 citedOpen Access
Redirection to the bone marrow improves T cell persistence and antitumor functions
Journal of Clinical Investigation·2018· 50 citedOpen Access
Human MHC Class I-restricted high avidity CD4<sup>+</sup>T cells generated by co-transfer of TCR and CD8 mediate efficient tumor rejection in vivo
OncoImmunology·2012· 49 citedOpen Access
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Frequent Co-authors

Cristina Lo Celso(18), Hans J. Stauss(10), Emma Morris(10), Myriam Haltalli(8), Mario Perro(8), Sara González Antón(8), Ronjon Chakraverty(7), Flora Birch(7), Michela Cesco-Gaspere(6), Angelika Holler(6), Dominique Bonnet(5), Sharyn Thomas(5), Shao‐An Xue(5), Reema Khorshed(5), Sara Ghorashian(5), Cécile Voisine(5), A Holler(5), Daniel P. Hart(4), Graham P. Wright(4), Maryam Ahmadi(4)