Megan Riel‐Mehan

Allen Institute for Cell Science — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

14h-index846citations25works0.02yr avg
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Research Topics

Cell Image Analysis Techniques(11), Gene Regulatory Network Analysis(6), Melanoma and MAPK Pathways(5), Synthesis and biological activity(4), Cellular Mechanics and Interactions(4)

Publications25 total

BPS2025 - Generative computational modeling with cellPACK reveals interplay between rules of intracellular organization and geometry in hiPSCs
Biophysical Journal·2025
BPS2025 - Generative computational modeling with CellPACK reveals interplay between rules of intracellular organization and geometry in hiPSCs
Biophysical Journal·2025
Advancing cell biology by unifying open-source modeling and facilitating broad community collaboration
Biophysical Journal·2024Open Access
Evaluating rules of intracellular organization in human-induced pluripotent stem cells using generative computational models via cellPACK
Biophysical Journal·2024Open Access
Building the next generation of virtual cells to understand cellular biology
Biophysical Journal·2023· 27 citedOpen Access
Integrated intracellular organization and its variations in human iPS cells
Nature·2023· 130 citedOpen Access
The Simularium Viewer: an interactive online tool for sharing spatiotemporal biological models
Nature Methods·2022· 16 citedOpen Access
Robust integrated intracellular organization of the human iPS cell: where, how much, and how variable
2020· 28 cited
Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes
eLife·2017· 140 citedOpen Access
New Pharmacogenomics Research Network: An Open Community Catalyzing Research and Translation in Precision Medicine
Clinical Pharmacology & Therapeutics·2017· 38 citedOpen Access
Author response: Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes
2017· 4 citedOpen Access
PSFC: a Pathway Signal Flow Calculator App for Cytoscape
F1000Research·2017· 17 citedOpen Access
Three-dimensional actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes
2017· 2 citedOpen Access
PSFC: a Pathway Signal Flow Calculator App for Cytoscape
F1000Research·2015· 13 citedOpen Access
cellPACK: A Virtual Mesoscope To Model and Visualize Structural Systems Biology
2015 AAAS Annual Meeting (12-16 February 2015)·2015
A Crosslinker Based on a Tethered Electrophile for Mapping Kinase-Substrate Networks
Chemistry & Biology·2014· 14 cited
Development of Chemical Crosslinkers to Trap-Substrate Pairs
eScholarship (California Digital Library)·2013Open Access
Abstract 3834: 3-ethynyl-1H-indazoles as inhibitors of PI3k signaling pathway
Cancer Research·2011
Design, Synthesis, and Structure−Activity Relationships of 3-Ethynyl-1<i>H</i>-indazoles as Inhibitors of the Phosphatidylinositol 3-Kinase Signaling Pathway
Journal of Medicinal Chemistry·2010· 30 citedOpen Access
Synthesis and optimization of thiadiazole derivatives as a novel class of substrate competitive c-Jun N-terminal kinase inhibitors
Bioorganic & Medicinal Chemistry·2009· 24 citedOpen Access
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Frequent Co-authors

Graham T. Johnson(13), Surya K. De(8), Maurizio Pellecchia(8), John L. Stebbins(5), Li‐Hsing Chen(5), Aras Emdadi(5), Blair Lyons(5), Julie A. Theriot(5), Russell Dahl(5), Elisa Barile(5), Vida Chen(5), Thomas Machleidt(4), Matheus P. Viana(4), Jason Cellitti(3), Lillian K. Fritz‐Laylin(3), Bi‐Chang Chen(3), Samuel J. Lord(3), Thomas D. Goddard(3), Thomas E. Ferrin(3), Eric Betzig(3)