Irene Lara‐Sáez

University College Dublin — Ireland

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index1.1kcitations48works17.82yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

RNA Interference and Gene Delivery(19), Virus-based gene therapy research(11), Silk-based biomaterials and applications(11), Hydrogels: synthesis, properties, applications(9), Advanced biosensing and bioanalysis techniques(7)

Publications48 total

Formulate a concentrated highly branched poly(β-amino ester)/DNA polyplex – one step closer to application in lung cystic fibrosis disease
Drug Development and Industrial Pharmacy·2025
Nonviral CRISPR/Cas9 mutagenesis for streamlined generation of mouse lung cancer models
Proceedings of the National Academy of Sciences·2024· 3 citedOpen Access
Highly branched poly β-amino ester/CpG-depleted CFTR plasmid nanoparticles for non-viral gene therapy in lung cystic fibrosis disease
Molecular Therapy — Methods & Clinical Development·2024· 6 citedOpen Access
Hyaluronic Acid/Chondroitin Sulfate-Based Dynamic Thiol–Aldehyde Addition Hydrogel: An Injectable, Self-Healing, On-Demand Dissolution Wound Dressing
Materials·2024· 6 citedOpen Access
EPS4.10 Developing a non-viral gene therapy strategy for treating lung cystic fibrosis disease
Journal of Cystic Fibrosis·2024
Unveiling the Role of Endoplasmic Reticulum Stress Pathways in Canine Demodicosis
Parasite Immunology·2024· 1 citedOpen Access
Cyclization-enhanced poly(β-amino ester)s vectors for efficient CRISPR gene editing therapy
Journal of Controlled Release·2024· 9 cited
Author response for "Unveiling the Role of Endoplasmic Reticulum Stress Pathways in Canine Demodicosis"
2024
Enhanced Strength for Double Network Hydrogel Adhesive Through Cohesion‐Adhesion Balance
Advanced Functional Materials·2024· 143 citedOpen Access
Backbone cationized highly branched poly(β-amino ester)s as enhanced delivery vectors in non-viral gene therapy
Journal of Controlled Release·2024· 10 citedOpen Access
“Non-viral CRISPR/Cas9 Mutagenesis for Streamlined Generation of Mouse Lung Cancer Models.”
2023· 3 citedOpen Access
CRISPR-Cas9-based non-viral gene editing therapy for topical treatment of recessive dystrophic epidermolysis bullosa
Molecular Therapy — Methods & Clinical Development·2023· 11 citedOpen Access
Guanidyl-Rich Poly(β Amino Ester)s for Universal Functional Cytosolic Protein Delivery and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) Cas9 Ribonucleoprotein Based Gene Editing
ACS Nano·2023· 28 citedOpen Access
Unveiling the Role of Endoplasmic Reticulum Stress Pathways in Canine Demodicosis
2023Open Access
3D Macrocyclic Structure Boosted Gene Delivery: Multi-Cyclic Poly(β-Amino Ester)s from Step Growth Polymerization
Journal of the American Chemical Society·2023· 33 citedOpen Access
Artificial Intelligence (AI)-Aided Structure Optimization for Enhanced Gene Delivery: The Effect of the Polymer Component Distribution (PCD)
ACS Applied Materials & Interfaces·2023· 20 citedOpen Access
WS17.04 Developing a non-viral gene therapy strategy for treating lung cystic fibrosis disease
Journal of Cystic Fibrosis·2023Open Access
Chitosan‐Based Hydrogels for Infected Wound Treatment
Macromolecular Bioscience·2023· 68 citedOpen Access
Gene expression analysis of Canine Demodicosis; A milieu promoting immune tolerance
Veterinary Parasitology·2023· 6 citedOpen Access
Enhanced gene transfection efficacy and safety through granular hydrogel mediated gene delivery process
Acta Biomaterialia·2023· 13 citedOpen Access
page 1 of 3Next →

Frequent Co-authors

Wenxin Wang(31), A Sigen(24), Zhonglei He(19), Yinghao Li(16), Xianqing Wang(15), Qian Xu(13), Dezhong Zhou(12), Rijian Song(11), Melissa Johnson(11), Jing Lyu(10), Ming Zeng(8), Bei Qiu(7), Zishan Li(6), Fatma Alshehri(5), Darío Manzanares(5), Lara Cutlar(5), W. Wang(5), Cameron Milne(4), Jack Creagh-Flynn(4), Jonathan O’Keeffe Ahern(4)