Khem Raj Ghusinga

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index691citations54works0.02yr avg
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Research Topics

Gene Regulatory Network Analysis(38), Bacterial Genetics and Biotechnology(17), Microbial Metabolic Engineering and Bioproduction(8), Probabilistic and Robust Engineering Design(7), RNA and protein synthesis mechanisms(5)

Publications54 total

Moment closure for uncertainty propagation in QSP models
2026Open Access
On moments and timing: stochastic analysis of biochemical systems
Library, Museums and Press - UDSpace (University of Delaware)·2024Open Access
Preclinical data exposures underpredict clinical physiologically active doses for bispecific TCEs in solid tumors indications; are there better metrics? - insights from a small mechanistic MBMA
2024Open Access
Towards a platform quantitative systems pharmacology (QSP) model for preclinical to clinical translation of antibody drug conjugates (ADCs)
Journal of Pharmacokinetics and Pharmacodynamics·2023· 24 citedOpen Access
Towards a platform quantitative systems pharmacology (QSP) model for preclinical to clinical translation of antibody drug conjugates (ADCs)
Research Square (Research Square)·2022· 2 citedOpen Access
A Stochastic model for RNA splicing
2022 European Control Conference (ECC)·2022
Feedback strategies for threshold crossing of protein levels at a prescribed time
2022 30th Mediterranean Conference on Control and Automation (MED)·2022· 4 cited
Threshold-crossing time statistics for gene expression in growing cells
2022Open Access
Threshold-crossing time statistics for size-dependent gene expression in growing cells
2022 American Control Conference (ACC)·2022· 4 cited
Regulatory strategies to schedule threshold crossing of protein levels at a prescribed time
2022· 4 citedOpen Access
Towards resolution of a paradox in plant G-protein signaling
PLANT PHYSIOLOGY·2021· 17 citedOpen Access
Comparing feedback strategies for minimizing noise in gene expression event timing
2021· 15 cited
Molecular switch architecture determines response properties of signaling pathways
Proceedings of the National Academy of Sciences·2021· 19 citedOpen Access
Reported differences in the flg22 response of the null mutation of AtRGS1 correlates with fixed genetic variation in the background of Col-0 isolates
Plant Signaling & Behavior·2021· 7 citedOpen Access
Regulating gene expression to achieve temporal precision
IFAC-PapersOnLine·2021· 2 citedOpen Access
Controlling event timing precision for gene expression with external disturbances
2020· 4 cited
Noise analysis in biochemical complex formation from stochastically produced components
2020· 1 cited
Molecular switch architecture drives response properties
2020· 4 citedOpen Access
Controlling Temporal Precision in Protein Levels with Dynamic External Disturbances
2020Open Access
Regulating gene expression to achieve temporal precision
2020· 1 citedOpen Access
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Frequent Co-authors

Abhyudai Singh(39), Andrew Lamperski(11), Cesar A. Vargas-García(8), Alan M. Jones(4), Timothy C. Elston(4), John J. Dennehy(3), César Nieto(3), Saurabh Modi(2), Bruna Scheuher(2), Kimiko McGirr(2), Maksymilian Nowak(2), Sheetal Panday(2), Joshua F. Apgar(2), Kalyanasundaram Subramanian(2), Alison Betts(2), Mohammad Soltani(2), Sairaj V. Dhople(2), Roger D. Jones(2), Madeline Smith(2), Zikai Xu(2)