Seth Blackshaw

Johns Hopkins University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

78h-index20.1kcitations380works4.42yr avg
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Research Topics

Retinal Development and Disorders(123), Neurogenesis and neuroplasticity mechanisms(43), Single-cell and spatial transcriptomics(43), Epigenetics and DNA Methylation(29), Circadian rhythm and melatonin(28)

Publications380 total

Ptbp1 is not required for retinal neurogenesis and cell fate specification
eLife·2025Open Access
Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis
Scientific Reports·2025Open Access
The long noncoding RNA <i>Peanut</i> ( <i>Gm11454</i> ) promotes neurogenesis and rod photoreceptor differentiation during postnatal retinal development
2025Open Access
Profiling the TRPV4 ankyrin repeat domain interactome and its disruption by neuromuscular disease-causing mutations
Journal of Biological Chemistry·2025Open Access
Author response: Ptbp1 is not required for retinal neurogenesis and cell fate specification
2025Open Access
MetaLigand provides a prior-knowledge-guided framework for predicting non-peptide ligand mediated cell-cell communication
Cell Reports Methods·2025Open Access
DIO3 coordinates photoreceptor development timing and fate stability in human retinal organoids
Genes & Development·2025· 1 citedOpen Access
Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels
2025Open Access
Blocking apoptosis promotes survival and alters developmental dynamics of human retinal ganglion cells in retinal organoids
2025Open Access
Ptbp1 is not required for retinal neurogenesis and cell fate specification
2025Open Access
Ptbp1 is not required for retinal neurogenesis and cell fate specification
eLife·2025Open Access
Comparative single-cell multiomic analysis reveals evolutionarily conserved and species-specific cellular mechanisms mediating natural retinal aging
2025Open Access
Sleep pressure is differentially regulated by molecularly distinct subtypes of Lhx6-positive and Lhx6-negative neurons of the zona incerta
2025Open Access
Ptbp1 is not required for retinal neurogenesis and cell fate specification
2025Open Access
Sleep need–dependent plasticity of a thalamic circuit promotes homeostatic recovery sleep
Science·2025· 18 cited
Decoding gene networks controlling hypothalamic and prethalamic neuron development
Cell Reports·2025· 10 citedOpen Access
Author response: Viral-mediated Pou5f1 (Oct4) overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia
2025Open Access
Viral-mediated Pou5f1 (Oct4) overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Müller glia
eLife·2025Open Access
Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis
2025· 1 citedOpen Access
Heterochronic transcription factor expression drives cone-dominant retina development in 13-lined ground squirrels
2025Open Access
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Frequent Co-authors

Solomon H. Snyder(15), Jiang Qian(10), Brian S. Clark(6), Heng Zhu(6), Jun Seop Jeong(5), Erin M. Poth(4), Constance L. Cepko(4), Clayton P. Santiago(4), Thanh Hoang(4), Dong Won Kim(4), Lizhi Jiang(4), Zhi Xie(4), Crystal C. Watkins(4), Herman Wolosker(3), Genevieve Stein-O’Brien(3), Thomas D. Sherman(3), Elana J. Fertig(3), Loyal A. Goff(3), Lizhi Jiang(3), Jianfei Hu(3)