Ornella Pellerito

Centre Hospitalier Universitaire Sainte-Justine — Canada

Medicine · Health Sciences

14h-index649citations37works6.02yr avg
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Research Topics

Cannabis and Cannabinoid Research(8), Autophagy in Disease and Therapy(7), Endoplasmic Reticulum Stress and Disease(7), Muscle Physiology and Disorders(4), Pancreatic function and diabetes(4)

Publications35 total

Bioactive lipid mediator class switching regulates myogenic cell progression and muscle regeneration
Nature Communications·2025· 7 citedOpen Access
Transcriptomic and lipidomic profiling reveals distinct bioactive lipid signatures in slow and fast muscles and highlights the role of resolvin‐ <scp>D2</scp> in fiber type determination during myogenesis
The FASEB Journal·2024· 5 citedOpen Access
Clearance of defective muscle stem cells by senolytics restores myogenesis in myotonic dystrophy type 1
Nature Communications·2023· 30 citedOpen Access
Clearance of defective muscle stem cells by senolytics reduces the expression of senescence-associated secretory phenotype and restores myogenesis in myotonic dystrophy type 1
2022· 1 citedOpen Access
Resolvin-D2 targets myogenic cells and improves muscle regeneration in Duchenne muscular dystrophy
Nature Communications·2021· 71 citedOpen Access
Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death
Cell Death and Disease·2019· 49 citedOpen Access
The Regenerative Potential of Amniotic Fluid Stem Cell Extracellular Vesicles: Lessons Learned by Comparing Different Isolation Techniques
Scientific Reports·2019· 79 citedOpen Access
Endoplasmic reticulum stress response is activated in pulmonary hypoplasia secondary to congenital diaphragmatic hernia, but is decreased by administration of amniotic fluid stem cells
Pediatric Surgery International·2018· 15 cited
Amniotic Fluid Stem-Cell Extracellular Vesicles Improve Pulmonary Vasculature in Experimental Congenital Diaphragmatic Hernia via the Release of RNA Cargo
Journal of the American College of Surgeons·2018· 2 cited
Changes in Drosophila mitochondrial proteins following chaperone-mediated lifespan extension confirm a role of Hsp22 in mitochondrial UPR and reveal a mitochondrial localization for cathepsin D
Mechanisms of Ageing and Development·2016· 18 cited
The secreted protein acidic and rich in cysteine is a critical mediator of cell death program induced by WIN/TRAIL combined treatment in osteosarcoma cells
International Journal of Oncology·2015· 14 citedOpen Access
WIN induces apoptotic cell death in human colon cancer cells through a block of autophagic flux dependent on PPARγ down-regulation
APOPTOSIS·2014· 48 cited
Involvement of PAR-4 in Cannabinoid-Dependent Sensitization of Osteosarcoma Cells to TRAIL-Induced Apoptosis
International Journal of Biological Sciences·2014· 40 citedOpen Access
Notch inhibition restores TRAIL-mediated apoptosis via AP1-dependent upregulation of DR4 and DR5 TRAIL receptors in MDA-MB-231 breast cancer cells
International Journal of Oncology·2013· 33 citedOpen Access
Synthesis, chemical characterization and biological activity of new histone acetylation/deacetylation specific inhibitors: A novel and potential approach to cancer therapy
Journal of Inorganic Biochemistry·2013· 13 cited
CCDC 830010: Experimental Crystal Structure Determination
The Cambridge Structural Database·2013Open Access
Cannabinoid-associated cell death mechanisms in tumor models
International Journal of Oncology·2012· 41 citedOpen Access
Autophagy and ER-stress participate to cannabinoid-induced apoptosis in colon carcinoma cells
2012
Different expression of PPARs in WIN-treated cells: the game of roles
2012
A comparison between the role of SPARC in osteogenic differentiation of mesenchymal stem cells and in WIN/TRAIL-induced apoptosis in osteosarcoma cells
2012
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Frequent Co-authors

Michela Giuliano(24), Giuseppe Calvaruso(20), Patrizia Portanova(14), Renza Vento(13), Antonietta Notaro(9), Giovanni Tesoriere(7), Selenia Sabella(7), Nicolas A. Dumont(5), Claudia Pellerito(5), Thomas Molina(4), Anna De Blasio(4), G Tesoriere(4), Lorenzo Pellerito(4), Girolamo Casella(4), Michelangelo Scopelliti(4), Lina Antounians(3), Augusto Zani(3), Junio Dort(3), Zakaria Orfi(3), Paul Fabre(3)