Daniel J. Termine

Whitehead Institute for Biomedical Research — United States

Medicine · Health Sciences

7h-index593citations9works0.02yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(3), Glycosylation and Glycoproteins Research(2), Cellular transport and secretion(2), Endoplasmic Reticulum Stress and Disease(2), Neuroscience and Neuropharmacology Research(1)

Publications9 total

Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment
Molecular Cell·2018· 276 citedOpen Access
Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment
DSpace@MIT (Massachusetts Institute of Technology)·2018Open Access
Inter-domain Communication of Human Cystathionine β-Synthase
Journal of Biological Chemistry·2014· 61 citedOpen Access
Splice isoform and pharmacological studies reveal that sterol depletion relocalizes α-synuclein and enhances its toxicity
Proceedings of the National Academy of Sciences·2014· 13 citedOpen Access
The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I
Journal of Cell Science·2009· 54 citedOpen Access
Small Molecules Block the Polymerization of Z α<sub>1</sub>-Antitrypsin and Increase the Clearance of Intracellular Aggregates
Journal of Medicinal Chemistry·2007· 127 citedOpen Access
Physical Interaction with EDEM1 hinders proteolytic down-regulation of human ER mannosidase I as a component of the mammalian UPR
The FASEB Journal·2007
Human Endoplasmic Reticulum Mannosidase I Is Subject to Regulated Proteolysis
Journal of Biological Chemistry·2006· 53 citedOpen Access
α1-Antitrypsin as model to assess glycan function in endoplasmic reticulum
Methods·2005· 9 cited

Frequent Co-authors

Richard N. Sifers(5), Susan Lindquist(3), Ying Wu(3), Saranna Fanning(2), Aftabul Haque(2), Thibaut Imberdis(2), Valeriya Baru(2), M. Inmaculada Barrasa(2), Silke Nuber(2), Nagendran Ramalingam(2), Gary P. H. Ho(2), Tallie Noble(2), Jackson Sandoe(2), Yali Lou(2), Dirk Landgraf(2), Yelena Freyzon(2), Gregory A. Newby(2), Frank Soldner(2), Elizabeth Terry-Kantor(2), Harald F. Hofbauer(2)