Yongfeng Tao

Scripps Research Institute — United States

Medicine · Health Sciences

10h-index571citations19works11.72yr avg
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Research Topics

Microbial Natural Products and Biosynthesis(6), Protein Degradation and Inhibitors(4), Cancer Cells and Metastasis(3), Glycosylation and Glycoproteins Research(3), Click Chemistry and Applications(3)

Publications19 total

Ophiobolin A impacts mitochondrial redox biology in an epithelial-mesenchymal transition (EMT)-specific manner
Cancer Cell International·2026Open Access
Ophiobolin A selectively alters mitochondria, metabolism and redox biology in breast cancer and mammary epithelial cells which have undergone epithelial to mesenchymal transition
2025Open Access
Proteomic Ligandability Maps of Spirocycle Acrylamide Stereoprobes Identify Covalent ERCC3 Degraders
Journal of the American Chemical Society·2024· 35 citedOpen Access
Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2
Angewandte Chemie International Edition·2023· 50 citedOpen Access
Chemical Proteomic Discovery of Isotype‐Selective Covalent Inhibitors of the RNA Methyltransferase NSUN2
Angewandte Chemie·2023Open Access
Correction to “Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1”
Journal of the American Chemical Society·2023· 1 cited
Therapeutic vulnerabilities of cancer stem cells and effects of natural products
Natural Product Reports·2023· 15 citedOpen Access
Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1
Journal of the American Chemical Society·2022· 120 citedOpen Access
Publisher Correction: A proteome-wide atlas of lysine-reactive chemistry
Nature Chemistry·2021· 3 citedOpen Access
A proteome-wide atlas of lysine-reactive chemistry
Nature Chemistry·2021· 239 citedOpen Access
Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A
Scientific Reports·2021· 18 citedOpen Access
Pharmacophore-Directed Retrosynthesis Applied to Ophiobolin A: Simplified Bicyclic Derivatives Displaying Anticancer Activity
Organic Letters·2020· 28 citedOpen Access
Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A
2020· 2 citedOpen Access
Abstract P4-07-10: Epithelial-mesenchymal transition sensitizes breast cancer cells to paraptosis-mediated cell death via the fungus-derived sesterpenoid, Ophiobolin A
Cancer Research·2019· 1 cited
Total Synthesis and Anticancer Activity of (+)‐Hypercalin C and Congeners
Angewandte Chemie International Edition·2019· 19 citedOpen Access
Total Synthesis and Anticancer Activity of (+)‐Hypercalin C and Congeners
Angewandte Chemie·2019· 10 cited
Quantitative chemoproteomic profiling reveals multiple target interactions of spongiolactone derivatives in leukemia cells
Chemical Communications·2017· 14 cited
ChemInform Abstract: Heck‐Type Cross‐Coupling Between Halo‐exo‐Glycals and endo‐Glycals: A Practical Way to Achieve C‐Glycosidic Disaccharides.
ChemInform·2014
Heck-type cross-coupling between halo-exo-glycals and endo-glycals: a practical way to achieve C-glycosidic disaccharides
Tetrahedron Letters·2013· 16 cited

Frequent Co-authors

Benjamin F. Cravatt(9), Joseph H. Taube(9), Daniel Romo(8), Keighley Reisenauer(7), Antonio Evidente(6), Bruno Melillo(5), Stuart L. Schreiber(5), Alexander Kornienko(5), David Remillard(4), Angela Boari(4), Evert Njomen(3), Jarrett R. Remsberg(3), Marco Masi(3), Alec Ingros(3), Jaquelin Aroujo(3), Mikail E. Abbasov(2), Madeline E. Kavanagh(2), Taka-Aki Ichu(2), Michael R. Lazear(2), Vincent M. Crowley(2)