Swathi Ayloo

AVEO Oncology (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index1.4kcitations22works0.72yr avg
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Research Topics

Microtubule and mitosis dynamics(5), Cellular transport and secretion(4), Barrier Structure and Function Studies(4), Caveolin-1 and cellular processes(4), Photosynthetic Processes and Mechanisms(3)

Publications22 total

Development of a secretable frataxin for enhanced efficacy in treating Friedreich’s Ataxia
Molecular Therapy Advances·2025Open Access
AAV gene therapy for GBA1-related diseases
Molecular Therapy·2025
Cross-species efficacy of AAV-mediated ARSA replacement for metachromatic leukodystrophy
Journal of Clinical Investigation·2025· 4 citedOpen Access
AAV gene therapy for GBA-PD and Gaucher Disease
2025
AAV-mediated ARSA replacement for the treatment of Metachromatic Leukodystrophy
2025· 1 citedOpen Access
Evaluation of a novel AAV capsid with widespread CNS and peripheral biodistribution in non-human primates
Molecular Genetics and Metabolism·2024Open Access
AAV-ARSA mediated gene replacement for the treatment of metachromatic leukodystrophy
Molecular Genetics and Metabolism·2024
Using single nuclear RNAseq to assess impact of AAV-ARSA gene therapy on oligodendrocyte populations
Molecular Genetics and Metabolism·2023
AAV-ARSA-mediated gene replacement for the treatment of metachromatic leukodystrophy
Molecular Genetics and Metabolism·2023
Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier
Neuron·2022· 149 citedOpen Access
Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier
2021· 9 citedOpen Access
Development and Cell Biology of the Blood-Brain Barrier
Annual Review of Cell and Developmental Biology·2019· 485 citedOpen Access
Transcytosis at the blood–brain barrier
Current Opinion in Neurobiology·2019· 278 citedOpen Access
Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes
Molecular Biology of the Cell·2017· 36 citedOpen Access
Molecular and Cellular Approaches Toward Understanding Dynein-Driven Motility
ScholarlyCommons (University of Pennsylvania)·2016Open Access
Optogenetic control of organelle transport using a photocaged chemical inducer of dimerization
Current Biology·2015· 78 citedOpen Access
Dynactin Functions as Both a Dynamic Tether and Brake during Dynein-Driven Motility
Biophysical Journal·2015· 2 citedOpen Access
Reconstitution of microtubule-based motility using cell extracts
Methods in cell biology·2015· 3 cited
Dynactin functions as both a dynamic tether and brake during dynein-driven motility
Nature Communications·2014· 98 citedOpen Access
Why I Do Science, Part II
2013
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Frequent Co-authors

Shyam Ramachandran(8), Martin Goulet(8), Jeffery Ardinger(6), Erika L.F. Holzbaur(5), Jie Bu(5), Mahmud Hossain(5), Christian Mueller(5), Chenghua Gu(4), Lilu Guo(4), Debabrata Ghosh(4), Shelley N. Chou(4), Shelley Nass(4), Bradford Elmer(4), M. Isabel Alcalá Ramos(3), Roger Trullo(3), Jessica M. Hogestyn(3), Amy M. Richards(3), Giorgio Gaglia(3), Catherine R. O’Riordan(3), Lydia Blatnik(3)