Amanda Johns

Neuroscience · Life Sciences

17h-index2.0kcitations38works0.02yr avg
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Research Topics

Sleep and Wakefulness Research(11), Sleep and related disorders(10), Regulation of Appetite and Obesity(10), Radical Photochemical Reactions(8), Synthesis and Reactivity of Heterocycles(4)

Publications38 total

Prevalence and Predictors of Early Response to Adjunct Methadone for Cancer-Related Pain in Palliative Care Patients—A Retrospective Study
Journal of Palliative Medicine·2025
The prevalence and predictors of discharge opioid overprescribing in opioid-naïve patients after breast, gynecologic, and head and neck cancer surgery: a prospective cohort study
Canadian Journal of Anesthesia/Journal canadien d anesthésie·2024Open Access
Phase I trial of metronomic oral topotecan in combination with pazopanib utilizing a daily dosing schedule to treat recurrent or persistent gynecologic tumors.
Journal of Clinical Oncology·2012· 5 cited
Acylglycinamides as inhibitors of glycine transporter type 1
Bioorganic & Medicinal Chemistry Letters·2011· 2 citedOpen Access
Abstract 4714: Phase I/II trial of ixabepilone (Ixa) and dasatinib (D) for treatment of metastatic breast cancer (MBC)
Cancer Research·2011· 3 cited
Acute hyperammonemic encephalopathy in adult onset ornithine transcarbamylase deficiency
Intensive Care Medicine·2008· 35 citedOpen Access
Phase I dosage-finding and pharmacokinetic (PK) study of intravenous topotecan and oral erlotinib in patients (pts) with refractory solid tumors
Journal of Clinical Oncology·2008· 1 cited
Acute hyperammonemic encephalopathy in adult onset ornithine transcarbamylase
2008
Satiety enhancement by selective orexin-1 receptor antagonist SB-334867: influence of test context and profile comparison with CCK-8S
Behavioural Brain Research·2004· 42 cited
Anorexia and weight loss in male rats 24h following single dose treatment with orexin-1 receptor antagonist SB-334867
Behavioural Brain Research·2004· 67 cited
Differential effects of the selective orexin-1 receptor antagonist SB-334867 and lithium chloride on the behavioural satiety sequence in rats
Physiology & Behavior·2004· 67 cited
Orexin‐A, an hypothalamic peptide with analgesic properties. (SmithKline Beecham Pharmaceuticals, Harlow, Essex, United Kingdom) <i>Pain.</i> 2001;92:81–90.
Pain Practice·2001· 1 cited
A Concise Enantioselective Synthesis of the AB Ring System of the Manzamine Alkaloids by Ring‐Closing Enyne Metathesis.
ChemInform·2001
1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor
Bioorganic & Medicinal Chemistry Letters·2001· 165 citedOpen Access
Orexin-A, an hypothalamic peptide with analgesic properties
Pain·2001· 266 cited
A concise enantioselective synthesis of the AB ring system of the manzamine alkaloids by ring-closing enyne metathesis
Tetrahedron Letters·2001· 30 cited
SB‐334867, a selective orexin‐1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin‐A in rats
European Journal of Neuroscience·2001· 230 cited
SB‐334867‐A: the first selective orexin‐1 receptor antagonist
British Journal of Pharmacology·2001· 312 citedOpen Access
Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX 1 ) receptors, with downstream 5-HT 2C receptor involvement
Psychopharmacology·2001· 93 cited
Effects of centrally administered orexin-B and orexin-A: a role for orexin-1 receptors in orexin-B-induced hyperactivity
Psychopharmacology·2001· 105 cited
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Frequent Co-authors

Rod A. Porter(8), John A. Murphy(8), N. Upton(6), Roderick A. Porter(4), Philip D. Jeffrey(4), R.J. Rodgers(4), Jason C. G. Halford(4), John E. Blundell(4), Michael S. Hadley(4), Martyn C. Coldwell(4), Graham J. Riley(4), Stephen Brough(3), A. Jackie Hunter(3), Yasuyuki Ishii(3), Izzy Boyfield(3), Emma E. Scott(3), Stephen A. Smith(3), Geoffrey Stemp(3), J. Stephen Clark(3), Robert J. Townsend(3)