Antao Chang

China Medical University — Taiwan

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index1.6kcitations80works7.42yr avg
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Research Topics

Cancer, Hypoxia, and Metabolism(12), Pancreatic and Hepatic Oncology Research(11), Cancer Cells and Metastasis(11), RNA modifications and cancer(10), PARP inhibition in cancer therapy(8)

Publications80 total

Targeting TNK2/ACK1 reverses the immunosuppressive tumor microenvironment and synergizes with immunochemotherapy in pancreatic cancer
Nature Communications·2025· 1 citedOpen Access
Tumor‐Derived Interleukin 35 Promotes Fibrosis in the Tumor Microenvironment of Pancreatic Cancer by Activating Pancreatic Stellate Cells
Advanced Science·2025Open Access
CLT-003 exerts anti-tumor activity in pancreatic cancer by blocking the PI3K/AKT/HIF-1α pathway
Cancer Biology and Medicine·2025Open Access
A CD147-targeted small-molecule inhibitor potentiates gemcitabine efficacy by triggering ferroptosis in pancreatic ductal adenocarcinoma
Cell Reports Medicine·2025· 3 citedOpen Access
Abstract 4418: Epigenetic reactivation of estrogen receptor for treatment of triple-negative breast cancer
Cancer Research·2025
Nociceptor neurons promote PDAC progression and cancer pain by interaction with cancer-associated fibroblasts and suppression of natural killer cells
Cell Research·2025· 38 citedOpen Access
Correction to: TIFA suppresses hepatocellular carcinoma progression via MALT1-dependent and -independent signaling pathways
Signal Transduction and Targeted Therapy·2025· 1 citedOpen Access
Research on precision treatment of pancreatic cancer targeted by antibody-drug conjugates
BioScience Trends·2025Open Access
BICC1 drives pancreatic cancer stemness and chemoresistance by facilitating tryptophan metabolism
Science Advances·2024· 26 citedOpen Access
Aberrant METTL14 gene expression contributes to malignant transformation of benzene-exposed myeloid cells
Ecotoxicology and Environmental Safety·2024Open Access
Abstract 4613: Tumor-derived interleukin 35 facilitates the gemcitabine resistance in pancreatic adenocarcinoma by mediating the dissemination of chemoresistance among PDAC cells
Cancer Research·2024
Targeting ESE3/EHF With Nifurtimox Inhibits CXCR2+ Neutrophil Infiltration and Overcomes Pancreatic Cancer Resistance to Chemotherapy and Immunotherapy
Gastroenterology·2024· 30 cited
Tumor-derived interleukin 35 mediates the dissemination of gemcitabine resistance in pancreatic adenocarcinoma
Oncogene·2024· 4 cited
Correction: BICC1 drives pancreatic cancer progression by inducing VEGF-independent angiogenesis
Signal Transduction and Targeted Therapy·2024· 1 citedOpen Access
Combination of RUNX1 inhibitor and gemcitabine mitigates chemo‐resistance in pancreatic ductal adenocarcinoma by modulating BiP/PERK/eIF2α-axis-mediated endoplasmic reticulum stress
Journal of Experimental & Clinical Cancer Research·2023· 24 citedOpen Access
RETRACTED ARTICLE: BICC1 drives pancreatic cancer progression by inducing VEGF-independent angiogenesis
Signal Transduction and Targeted Therapy·2023· 43 citedOpen Access
Nuclear PLD1 combined with NPM1 induces gemcitabine resistance through tumorigenic IL7R in pancreatic adenocarcinoma
Cancer Biology and Medicine·2023· 8 citedOpen Access
Combination of RUNX1 inhibitor and gemcitabine to mitigate chemo‐resistance in pancreatic ductal adenocarcinoma by modulating BiP/PERK/eIF2a-axis-mediated endoplasmic reticulum stress
Research Square (Research Square)·2023Open Access
Irbesartan overcomes gemcitabine resistance in pancreatic cancer by suppressing stemness and iron metabolism via inhibition of the Hippo/YAP1/c-Jun axis
Journal of Experimental & Clinical Cancer Research·2023· 74 citedOpen Access
Survival outcomes of neoadjuvant therapy followed by radical resection versus upfront surgery for stage I–III pancreatic ductal adenocarcinoma: a retrospective cohort study
International Journal of Surgery·2023· 10 citedOpen Access
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Frequent Co-authors

Chongbiao Huang(21), Rong Xiang(21), Jihui Hao(19), Tiansuo Zhao(17), Xiuchao Wang(16), Peiqing Sun(16), Yanan Chen(10), Guanwen Wang(9), Shuang Yang(8), Zengxun Li(8), Shengyu Yang(8), Song Gao(8), Wenzhi Shen(8), Jing Liu(8), Yongjie Xie(7), Ruifang Gao(7), Tianxing Zhou(6), Juan Wang(6), Dongmei Cheng(6), Hongwei Wang(6)