Shawn H. Pfeil

West Chester University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index816citations23works0.02yr avg
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Research Topics

DNA and Nucleic Acid Chemistry(5), Force Microscopy Techniques and Applications(5), Protein Structure and Dynamics(4), Advanced biosensing and bioanalysis techniques(4), Photonic and Optical Devices(4)

Publications23 total

N-methyl mesoporphorin IX, a reporter on GQ-DNA, forms a dimer in aqueous solution
Biophysical Journal·2024
Erratum to “Homopurine guanine-rich sequences in complex with N-methylmesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad” [Bioorg. Med. Chem. 77 (2023) 117112]
Bioorganic & Medicinal Chemistry·2023
Homopurine guanine-rich sequences in complex with N-methyl mesoporphyrin IX form parallel G-quadruplex dimers and display a unique symmetry tetrad
Bioorganic & Medicinal Chemistry·2022· 5 citedOpen Access
Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy
Journal of Visualized Experiments·2020· 3 citedOpen Access
Fabrication of Zero Mode Waveguides for High Concentration Single Molecule Microscopy
Journal of Visualized Experiments·2020
Nanoaperture fabrication via colloidal lithography for single molecule fluorescence analysis
PLoS ONE·2019· 24 citedOpen Access
Nanoaperture fabrication via colloidal lithography for single molecule fluorescence imaging
2019· 2 citedOpen Access
Folding Kinetics of Human Telomeric G Quadruplex (HTG) Sequence
Bulletin of the American Physical Society·2018
Size and Fluorescence characterization of Silicon Nanoparticles for Sensing Applications.
Bulletin of the American Physical Society·2018
E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form
Nucleic Acids Research·2018· 25 citedOpen Access
A Colloidal Lithography and Catalyzed Growth Approach to Semiconducting Nanowire Sensors
Bulletin of the American Physical Society·2016
Simple thermal treatment for the size control of pore arrays in a polystyrene colloidal crystal films
Bulletin of the American Physical Society·2016
Role of Denatured-State Properties in Chaperonin Action Probed by Single-Molecule Spectroscopy
Biophysical Journal·2014· 4 citedOpen Access
A comparison of the folding kinetics of a small, artificially selected DNA aptamer with those of equivalently simple naturally occurring proteins
Protein Science·2013· 14 citedOpen Access
Microfluidic mixer designed for performing single-molecule kinetics with confocal detection on timescales from milliseconds to minutes
Nature Protocols·2013· 88 cited
Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy
Nature Communications·2012· 130 citedOpen Access
Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy
Proceedings of the National Academy of Sciences·2012· 336 citedOpen Access
Maximizing Photon Counts and Time Resolution for Single Molecule Fluorescence Studies in Micro Fluidic Mixing System
Biophysical Journal·2011Open Access
Single-molecule spectroscopy of protein folding in a chaperonin cage
Proceedings of the National Academy of Sciences·2010· 122 citedOpen Access
Tracking a Molecular Motor with a Nanoscale Optical Encoder
Nano Letters·2010· 11 citedOpen Access
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Frequent Co-authors

Everett A. Lipman(9), Yale E. Goldman(6), Daniel Nettels(5), Armin Hoffmann(5), Benjamin Schuler(5), Ryan M. Jamiolkowski(5), Shane A. Fiorenza(5), Alyssa M. Tate(5), Kevin Y. Chen(4), Hagen Hofmann(3), C. E. Wickersham(3), Kevin W. Plaxco(3), Liliya A. Yatsunyk(3), Andrea Soranno(2), Frank Hillger(2), Kevin J. Cash(2), Irina Bruck(2), Daniel L. Kaplan(2), Ming Ye(2), Erin Chen(2)