Francesco De Marchis

Vita-Salute San Raffaele University — Italy

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index4.1kcitations34works14.52yr avg
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Research Topics

Advanced Glycation End Products research(18), Immune Response and Inflammation(12), S100 Proteins and Annexins(8), Inflammatory mediators and NSAID effects(6), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(5)

Publications33 total

Fibroblast-like cells in mesothelioma can derive from tumor cells
Cell Death and Differentiation·2025Open Access
The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with CXCL12
Nature Communications·2024· 29 citedOpen Access
The acidic intrinsically disordered region of the inflammatory mediator HMGB1 mediates fuzzy interactions with chemokine CXCL12
2023· 1 citedOpen Access
Pamoic acid is an inhibitor of HMGB1·CXCL12 elicited chemotaxis and reduces inflammation in murine models of Pseudomonas aeruginosa pneumonia
Molecular Medicine·2022· 14 citedOpen Access
Pamoic acid is an inhibitor of HMGB1•CXCL12 elicited chemotaxis and reduces inflammation in murine models of Pseudomonas aeruginosa pneumonia
2022Open Access
CXCR4 engagement triggers CD47 internalization and antitumor immunization in a mouse model of mesothelioma
EMBO Molecular Medicine·2021· 22 citedOpen Access
Discovery of 5,5′-Methylenedi-2,3-Cresotic Acid as a Potent Inhibitor of the Chemotactic Activity of the HMGB1·CXCL12 Heterocomplex Using Virtual Screening and NMR Validation
Frontiers in Chemistry·2020· 10 citedOpen Access
Discovery of 5,5’-methylenedi-2,3-cresotic acid as a potent inhibitor of chemotactic activity of the HMGB1•CXCL12 heterocomplex using Virtual Screening and NMR validation
2020· 2 citedOpen Access
Diflunisal targets the <scp>HMGB</scp> 1/ <scp>CXCL</scp> 12 heterocomplex and blocks immune cell recruitment
EMBO Reports·2019· 47 citedOpen Access
Diflunisal targets the HMGB1/CXCL12 heterocomplex and blocks immune cell recruitment
2019· 12 citedOpen Access
High mobility group box 1 orchestrates tissue regeneration via CXCR4
The Journal of Experimental Medicine·2017· 146 citedOpen Access
Non-oxidizable HMGB1 induces cardiac fibroblasts migration via CXCR4 in a CXCL12-independent manner and worsens tissue remodeling after myocardial infarction
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2017· 51 cited
Human malignant mesothelioma is recapitulated in immunocompetent BALB/c mice injected with murine AB cells
Scientific Reports·2016· 39 citedOpen Access
Aspirin delays mesothelioma growth by inhibiting HMGB1-mediated tumor progression
Cell Death and Disease·2015· 80 citedOpen Access
Aspirin’s Active Metabolite Salicylic Acid Targets High Mobility Group Box 1 to Modulate Inflammatory Responses
Molecular Medicine·2015· 118 citedOpen Access
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release
The Journal of General Physiology·2012· 5 cited
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release
The Journal of General Physiology·2012· 13 cited
Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release
The Journal of Experimental Medicine·2012· 693 citedOpen Access
HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4
The Journal of Experimental Medicine·2012· 651 citedOpen Access
The FGF-2-Derived Peptide FREG Inhibits Melanoma Growth In Vitro and In Vivo
Molecular Therapy·2010· 16 citedOpen Access
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Frequent Co-authors

Marco E. Bianchi(27), Alessandro Preti(10), Giovanna Musco(10), Federica De Leo(8), Giacomo Quilici(8), Maura Casalgrandi(7), Emilie Vénéreau(6), Roberta Palumbo(6), Maurizio C. Capogrossi(6), Rosanna Mezzapelle(6), Malisa Vittoria Mantonico(6), Antonio Facchiano(5), Massimo P. Crippa(5), Milena Schiraldi(4), Angela Bachi(4), Mariagrazia Uguccioni(4), Tobias Pusterla(4), Angela Cattaneo(3), Jaron Liu(3), Lorenzo Raeli(3)