Helen A. Baghdoyan

University of Tennessee at Knoxville — United States

Neuroscience · Life Sciences

46h-index6.0kcitations168works0.82yr avg
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Research Topics

Sleep and Wakefulness Research(107), Neuroscience and Neuropharmacology Research(64), Sleep and related disorders(32), Circadian rhythm and melatonin(28), Neuroscience of respiration and sleep(24)

Publications168 total

Dose-dependent, opioid-induced sleep disruption is partially mediated by motor activity but not by body temperature in C57BL/6J mice
Journal of Pharmacology and Experimental Therapeutics·2025Open Access
Dose-dependent, opioid-induced sleep disruption is partially mediated by motor activity but not by body temperature in C57BL/6J mice
2025· 1 citedOpen Access
Fentanyl-Induced Suppression of NREM Sleep in C57BL/6J (B6) Mice Is Decreased by Pretreatment with an Orexin-2 Receptor (OX2R) Antagonist (Abstract ID: 191060)
Journal of Pharmacology and Experimental Therapeutics·2025
Machine learning and confirmatory factor analysis show that buprenorphine alters motor and anxiety-like behaviors in male, female, and obese C57BL/6J mice
Journal of Neurophysiology·2024· 2 citedOpen Access
Buprenorphrine Alters Anxiety-like Behavior in C57BL/6J (B6) Mice as a Function of Dose, Sex, and Obesity
Journal of Pharmacology and Experimental Therapeutics·2024· 1 cited
Gain Modulation by Mouse Prefrontal Cortex Diminishes Fentanyl-Induced Respiratory Depression
Journal of Pharmacology and Experimental Therapeutics·2023Open Access
Mediation Analysis Reveals that Opioid-Induced Sleep Disruption is Partially Mediated by Increased Motor Activity in C57BL/6J (B6) Mice
Journal of Pharmacology and Experimental Therapeutics·2023Open Access
Morphine and high-fat diet differentially alter the gut microbiota composition and metabolic function in lean versus obese mice
ISME Communications·2022· 16 citedOpen Access
Fentanyl and neostigmine delivered to mouse prefrontal cortex differentially alter breathing
Respiratory Physiology & Neurobiology·2022
Opioid‐Induced Respiratory Depression (OIRD) in C57BL/6J (B6) Mice is Mitigated by Prefrontal Cortex Neostigmine Administration
The FASEB Journal·2022
Fentanyl‐Induced Sleep Disruption in C57BL/6J (B6) Mice is not Secondary to Increased Motor Activity or Hypothermia
The FASEB Journal·2022· 2 cited
Buprenorphine differentially alters breathing among four congenic mouse lines as a function of dose, sex, and leptin status
Respiratory Physiology & Neurobiology·2021· 6 citedOpen Access
Opioids cause dissociated states of consciousness in C57BL/6J mice
Journal of Neurophysiology·2021· 16 cited
Prefrontal Cortex Metabolome Is Modified by Opioids, Anesthesia, and Sleep
Physiology·2021· 4 citedOpen Access
Fentanyl and Morphine Cause Dose‐Dependent Sleep Disruption in C57BL/6J (B6) Mice
The FASEB Journal·2021· 6 cited
Neostigmine Microinjected into Prefrontal Cortex of C57BL/6J (B6) Mice Stimulates Breathing
The FASEB Journal·2021· 2 cited
Fentanyl, but not Morphine, Increases Cortical Electroencephalographic (EEG) Delta Power during Wakefulness in C57BL/6J (B6) Mice
The FASEB Journal·2021· 3 cited
Neuronal mechanisms underlying opioid-induced respiratory depression: our current understanding
Journal of Neurophysiology·2021· 100 citedOpen Access
Isoflurane anesthesia disrupts the cortical metabolome
Figshare·2021Open Access
Isoflurane anesthesia disrupts the cortical metabolome
Journal of Neurophysiology·2020· 18 citedOpen Access
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Frequent Co-authors

Ralph Lydic(39), J. Allan Hobson(5), Christopher J.E. Watson(5), John C. Keifer(5), Giancarlo Vanini(4), Margarita L. Rodrigo‐Angulo(3), Robert W. McCarley(3), Jacqueline Vázquez(2), Christopher L. Douglas(2), Christal G. Coleman(2), Vasiliki J. Mallios(2), Anthony P. Monaco(1), F Assens(1), Clifton W. Callaway(1), Christa J. Van Dort(1), A. Urban Höglund(1), Jan‐Marino Ramirez(1), Nicholas J. Burgraff(1), Aguan Wei(1), Nathan A. Baertsch(1)