Aintzane García‐Bea

Faes Farma (Spain) — Spain

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index734citations23works1.32yr avg
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Research Topics

Receptor Mechanisms and Signaling(8), Neuroscience and Neuropharmacology Research(7), Tryptophan and brain disorders(6), Neurotransmitter Receptor Influence on Behavior(3), Vitamin D Research Studies(3)

Publications23 total

Analysis of the Efficacy and Safety of Weekly Calcifediol 100 µg in Vitamin D Deficient Patients
Journal of Clinical Medicine·2025Open Access
A Randomized Phase II/III Trial Evaluating the Efficacy and Safety of 100 and 125 µg of Calcifediol Weekly Treatment of Severe Vitamin D Deficiency
Nutrients·2025· 2 citedOpen Access
Efficacy and Safety of Weekly Calcifediol Formulations (75 and 100 µg) in Subjects with Vitamin D Deficiency: A Phase II/III Randomised Trial
Nutrients·2024· 2 citedOpen Access
Application of a dual mechanistic approach to support bilastine dose selection for older adults
CPT Pharmacometrics & Systems Pharmacology·2021· 11 citedOpen Access
Opposite alterations of 5HT2A receptor brain density in subjects with schizophrenia: relevance of radiotracers pharmacological profile
Translational Psychiatry·2021· 21 citedOpen Access
Di-aryl guanidinium derivatives: Towards improved α2-Adrenergic affinity and antagonist activity
European Journal of Medicinal Chemistry·2020· 5 citedOpen Access
Pharmacokinetics and safety of bilastine in children aged 6 to 11 years with allergic rhinoconjunctivitis or chronic urticaria
European Journal of Pediatrics·2020· 16 citedOpen Access
Bioequivalence Evaluation of Three Pediatric Oral Formulations of Bilastine in Healthy Subjects: Results from a Randomized, Open Label, Crossover Study
European Journal of Drug Metabolism and Pharmacokinetics·2019· 8 cited
Serotonin 5-HT2A receptor expression and functionality in postmortem frontal cortex of subjects with schizophrenia: Selective biased agonism via Gαi1-proteins
European Neuropsychopharmacology·2019· 53 citedOpen Access
Efficacy and safety of bilastine in reducing pruritus in patients with chronic spontaneous urticaria and other skin diseases: an exploratory study
Journal of Dermatological Treatment·2019· 24 citedOpen Access
Human cerebral 5-HT2A receptor labelling with [18F]altanserin, [3H]LSD, and [3H]M100907. Relevance of radiotracer intrinsic activity
European Neuropsychopharmacology·2019
Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects
Nature Neuroscience·2017· 101 citedOpen Access
A group II metabotropic glutamate receptor 3 (mGlu3, GRM3) isoform implicated in schizophrenia interacts with canonical mGlu3 and reduces ligand binding
Journal of Psychopharmacology·2017· 9 citedOpen Access
Substituted conformationally restricted guanidine derivatives: Probing the α2-adrenoceptors’ binding pocket
European Journal of Medicinal Chemistry·2016· 19 citedOpen Access
Metabotropic glutamate receptor 3 (mGlu3; mGluR3; GRM3) in schizophrenia: Antibody characterisation and a semi-quantitative western blot study
Schizophrenia Research·2016· 25 citedOpen Access
Allosteric signaling through an mGlu2 and 5-HT<sub>2A</sub>heteromeric receptor complex and its potential contribution to schizophrenia
Science Signaling·2016· 110 citedOpen Access
Novel Targets for Drug Treatment in Psychiatry
2016
P.3.a.001 Selective up-regulation of serotonin 5-HT2A receptor coupling to Gαi1-proteins in postmortem brain of subjects with schizophrenia
European Neuropsychopharmacology·2014· 1 cited
P.1.g.031 Functional coupling of group II metabotropic glutamate receptors to Gα-proteins in postmortem frontal cortex of schizophrenic subjects
European Neuropsychopharmacology·2013
P.1.g.022 Hallucinogenic and non-hallucinogenic 5-HT2A receptor agonists induce distinct patterns of G protein coupling in postmortem human brain
European Neuropsychopharmacology·2013· 4 cited
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Frequent Co-authors

J. Javier Meana(10), Javier González‐Maeso(10), Luís F. Callado(9), Patrícia Miranda-Azpiazu(7), Rebeca Dı́ez-Alarcia(6), Ane M. Gabilondo(5), Carolina Muguruza(5), Mitsumasa Kurita(4), Alexey Kozlenkov(4), José L. Moreno(4), Cristina Campo(4), Terrell Holloway(3), Scott J. Russo(3), Benito Morentín(3), Luis Labeaga(3), José-Luis Pérez-Castrillón(3), Esteban Jódar(3), Cristina Martínez Ostalé(3), Inmaculada Gilaberte(3), Giuseppe Mocci(2)