Regina M. Young

California University of Pennsylvania — United States

Medicine · Health Sciences

39h-index13.7kcitations138works4.82yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

CAR-T cell therapy research(115), Viral Infectious Diseases and Gene Expression in Insects(29), Virus-based gene therapy research(21), Immune Cell Function and Interaction(14), Cancer Immunotherapy and Biomarkers(12)

Publications138 total

Dual-targeted ping-pong CAR T cells: Leveraging peripheral expansion to improve solid tumor immunotherapy
Proceedings of the National Academy of Sciences·2025Open Access
Supplementary Tables and Figures from Anti-BCMA/CD19 CAR T Cells with Early Immunomodulatory Maintenance for Multiple Myeloma Responding to Initial or Later-Line Therapy
2025Open Access
IL-9 signaling redirects CAR T cell fate toward CD8+ memory and CD4+ cycling states, enhancing antitumor efficacy
Immunity·2025· 2 cited
Ping-pong dual CAR T cells: antigen-specific peripheral expansion of dual-targeted CAR T cells boosts antitumor immunity against solid tumors 2126
The Journal of Immunology·2025Open Access
IL-9 signaling enhances CAR T cell antitumor efficacy in solid tumors by promoting memory phenotypes and reducing dysfunction under antigen stress 2144
The Journal of Immunology·2025Open Access
Data from CAR Binders Affect CAR T-cell Tonic Signaling, Durability, and Sensitivity to Target
2025Open Access
Supplemental Figure 1 from CAR Binders Affect CAR T-cell Tonic Signaling, Durability, and Sensitivity to Target
2025Open Access
Supplementary Data from CAR Binders Affect CAR T-cell Tonic Signaling, Durability, and Sensitivity to Target
2025Open Access
Supplemental Figure 2 from CAR Binders Affect CAR T-cell Tonic Signaling, Durability, and Sensitivity to Target
2025Open Access
Supplemental Figure 4 from CAR Binders Affect CAR T-cell Tonic Signaling, Durability, and Sensitivity to Target
2025Open Access
Supplementary Data from CAR Binders Affect CAR T-cell Tonic Signaling, Durability, and Sensitivity to Target
2025Open Access
Supplemental Figure 3 from CAR Binders Affect CAR T-cell Tonic Signaling, Durability, and Sensitivity to Target
2025Open Access
Quadruple adenine base–edited allogeneic CAR T cells outperform CRISPR/Cas9 nuclease–engineered T cells
Proceedings of the National Academy of Sciences·2025· 18 citedOpen Access
CAR Binders Affect CAR T-cell Tonic Signaling, Durability, and Sensitivity to Target
Cancer Immunology Research·2025· 1 citedOpen Access
Abstract 4806: CAR binders affect CAR T cell tonic signaling, durability, and sensitivity to target
Cancer Research·2025
IL-9 signaling redirects CAR T cell fate toward CD8+ memory and CD4+ cycling states, enhancing anti-tumor efficacy
2025· 2 citedOpen Access
TET2 regulates early and late transitions in exhausted CD8 <sup>+</sup> T cell differentiation and limits CAR T cell function
Science Advances·2024· 18 citedOpen Access
788 Enhancing chimeric antigen receptor T Cell therapy with precision proton radiotherapy
Regular and Young Investigator Award Abstracts·2024Open Access
237 Enhancing mesothelin-directed CAR T cell therapy for unresectable or metastatic pancreatic adenocarcinoma
Regular and Young Investigator Award Abstracts·2024· 1 citedOpen Access
259 Dual-targeted CAR T cells boost antitumor immunity against solid tumors
Regular and Young Investigator Award Abstracts·2024· 1 citedOpen Access
page 1 of 7Next →

Frequent Co-authors

Carl H. June(37), Simon F. Lacey(24), J. Joseph Melenhorst(21), Bruce L. Levine(19), Irina Kulikovskaya(14), John Scholler(13), Megan M. Davis(12), Jennifer L. Brogdon(12), Joseph A. Fraietta(11), Wei‐Ting Hwang(8), Minnal Gupta(8), David L. Porter(8), Edward A. Stadtmauer(8), Adam D. Cohen(8), Gabriela Plesa(8), Michael C. Milone(8), David E Ambrose(7), Lifeng Tian(7), Alfred L. Garfall(7), Dan T. Vogl(7)