Ioannis Gelis

University of South Florida — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index1.5kcitations36works3.32yr avg
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Research Topics

Protein Structure and Dynamics(13), Heat shock proteins research(9), Enzyme Structure and Function(7), RNA and protein synthesis mechanisms(5), Antibiotic Resistance in Bacteria(4)

Publications36 total

Dynamic signature of activity-stability tradeoff in lactamase evolution
Nature Communications·2026Open Access
Biophysical Insights into the Binding Interactions of Inhibitors (ICA-1S/1T) Targeting Protein Kinase C-ι
Biophysica·2025Open Access
Biophysical Insights into the Binding Interactions of Inhibitors (ICA-1S/1T) Targeting Protein Kinase C-ι
Preprints.org·2025· 1 citedOpen Access
Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB
eLife·2024· 15 citedOpen Access
Second international symposium on the chaperone code, 2023
Cell Stress and Chaperones·2024· 4 citedOpen Access
Author response: Staphylococcus aureus FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB
2024Open Access
<i>Staphylococcus aureus</i> FtsZ and PBP4 bind to the conformationally dynamic N-terminal domain of GpsB
2022· 7 citedOpen Access
A unique class of Zn2+-binding serine-based PBPs underlies cephalosporin resistance and sporogenesis in Clostridioides difficile
Nature Communications·2022· 26 citedOpen Access
Assembly mechanism of early Hsp90-Cdc37-kinase complexes
Science Advances·2022· 29 citedOpen Access
Synthesis of paramagnetic ligands that target the C-terminal binding site of Hsp90
Bioorganic & Medicinal Chemistry Letters·2020· 4 citedOpen Access
Mechanism of proton transfer in class A β-lactamase catalysis and inhibition by avibactam
Proceedings of the National Academy of Sciences·2020· 50 citedOpen Access
Characterization of Arylalkylamine <i>N</i>-Acyltransferase from <i>Tribolium castaneum</i>: An Investigation into a Potential Next-Generation Insecticide Target
ACS Chemical Biology·2020· 15 cited
Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1
Nature Communications·2019· 61 citedOpen Access
Phosphorylation induced cochaperone unfolding promotes kinase recruitment and client class-specific Hsp90 phosphorylation
Nature Communications·2018· 52 citedOpen Access
<sup>1</sup>H NMR, <sup>1</sup>H–<sup>1</sup>H 2D TOCSY and GC-MS analyses for the identification of olive oil in Early Bronze Age pottery from Castelluccio (Noto, Italy)
Analytical Methods·2018· 27 citedOpen Access
Molecular insights into the interaction of Hsp90 with allosteric inhibitors targeting the C-terminal domain
MedChemComm·2018· 19 citedOpen Access
Yes1 kinase SH3 domain
Journal of Back and Musculoskeletal Rehabilitation·2018Open Access
C-terminal domain of Cdc37 co-chaperone, unfolded in the presence of 8M Urea.
Journal of Back and Musculoskeletal Rehabilitation·2018Open Access
Yes1 SH2 domain in complex with Cdc37-derived phosphopeptide
Journal of Back and Musculoskeletal Rehabilitation·2018Open Access
Acetyl group coordinated progression through the catalytic cycle of an arylalkylamine N-acetyltransferase
PLoS ONE·2017· 11 citedOpen Access
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Frequent Co-authors

Dimitra Keramisanou(22), Radwan Ebna Noor(10), Ashleigh Bachman(7), Yu Chen(6), Spyridoula Karamanou(5), Anastassios Economou(5), Charalampos G. Kalodimos(5), Adam A. Aboalroub(5), Ziming Zhang(5), Giorgos Gouridis(4), M. Trent Kemp(4), M. Sacco(4), Lauren R. Hammond(4), Prahathees J. Eswara(4), Claudio Luchinat(3), Vasantha Kumar M. V.(3), Brian S. J. Blagg(3), James W. Leahy(3), Dipanwita Bhattacharya(3), Jesper J. Madsen(3)