George T. De Sanctis

Sanofi (United States) — United States

Medicine · Health Sciences

34h-index5.2kcitations55works0.02yr avg
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Research Topics

Asthma and respiratory diseases(32), Immune Cell Function and Interaction(13), IL-33, ST2, and ILC Pathways(10), Neuroscience of respiration and sleep(8), Respiratory Support and Mechanisms(5)

Publications55 total

Role of cathepsin S in ozone-induced airway hyperresponsiveness and inflammation
Pulmonary Pharmacology & Therapeutics·2008· 33 citedOpen Access
Ventilatory responses to acute hypoxia in neurokinin-1 receptor deficient mice
Respiratory Physiology & Neurobiology·2007· 7 cited
Low-Level Subchronic Exposure to Wood Smoke Exacerbates Inflammatory Responses in Allergic Rats
Toxicological Sciences·2005· 41 citedOpen Access
Erratum: Role of cathepsin S-dependent epithelial cell apoptosis in IFN-γ-induced alveolar remodeling and pulmonary emphysema (Journal of Immunology (2005) 174 (8106-8115))
The Journal of Immunology·2005
The IL-6R α chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo
Journal of Clinical Investigation·2005· 1 cited
The IL-6R α chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo
Journal of Clinical Investigation·2005· 303 citedOpen Access
The IL-6R α chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo
Journal of Clinical Investigation·2005· 334 cited
Treg development and function during allergic airway inflammation in vivo
2005
Nitric oxide synthase‐2 down‐regulates surfactant protein‐B expression and enhances endotoxin‐induced lung injury in mice
The FASEB Journal·2004· 33 cited
Expression of nitric oxide synthase-2 in the lungs decreases airway resistance and responsiveness
Journal of Applied Physiology·2004· 49 cited
Lipoxins and Aspirin-Triggered Lipoxins in Airway Responses
Advances in experimental medicine and biology·2003· 16 cited
Molecular Characterization of Antigen‐Induced Lung Inflammation in a Murine Model of Asthma
Annals of the New York Academy of Sciences·2002· 10 cited
Bax is Crucial for IFN-γ-Induced Resolution of Allergen- Induced Mucus Cell Metaplasia
The Journal of Immunology·2002· 32 cited
Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A4
Nature Medicine·2002· 352 cited
Differential Effects of Ebselen on Neutrophil Recruitment, Chemokine, and Inflammatory Mediator Expression in a Rat Model of Lipopolysaccharide-Induced Pulmonary Inflammation
The Journal of Immunology·2002· 75 citedOpen Access
IFN-γ, But Not Fas, Mediates Reduction of Allergen-Induced Mucous Cell Metaplasia by Inducing Apoptosis
The Journal of Immunology·2002· 53 citedOpen Access
Development of Spontaneous Airway Changes Consistent with Human Asthma in Mice Lacking T-bet
Science·2002· 625 cited
Genetics of allergen-induced asthma
Journal of Allergy and Clinical Immunology·2001· 17 citedOpen Access
Evaluation of the Substrate Specificity of Human Mast Cell Tryptase βI and Demonstration of Its Importance in Bacterial Infections of the Lung
Journal of Biological Chemistry·2001· 145 citedOpen Access
Treatment of Allergic Airway Inflammation and Hyperresponsiveness by Antisense-Induced Local Blockade of Gata-3 Expression
The Journal of Experimental Medicine·2001· 236 citedOpen Access
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Frequent Co-authors

Jeffrey M. Drazen(24), Patricia W. Finn(9), Lester Kobzik(9), Francis H. Y. Green(7), Chandri Yandava(7), Aiping Jiao(7), Hartmut Grasemann(6), Eric S. Silverman(5), James A. MacLean(5), David A. Mark(5), David L. Perkins(5), F. H. Green(5), Susetta Finotto(4), Markus F. Neurath(4), Shixin Qin(4), Kate G. Ackerman(4), Peter R. Galle(4), David R. Beier(4), Walter W. Wolyniec(4), Manuela Cernadas(4)