Christian Espinosa‐Bustos

Pontificia Universidad Católica de Chile — Chile

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

16h-index644citations62works2.02yr avg
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Research Topics

Bioactive Compounds and Antitumor Agents(11), Synthesis and Biological Evaluation(10), Trypanosoma species research and implications(9), Crystallization and Solubility Studies(8), X-ray Diffraction in Crystallography(8)

Publications62 total

Experimental and In Silico Studies to Unravel the Antioxidant and Antibacterial Properties of Lichen Metabolites from Pseudocyphellaria compar and Pseudocyphellaria nudata
Antioxidants·2025Open Access
Buddleja globosa Leaf Methanolic Extract Acts Against Trypanosoma cruzi Parasites by Inducing Mitochondrial Inner Membrane Hyperpolarization
Plants·2025Open Access
3D-QSAR Design of New Bcr-Abl Inhibitors Based on Purine Scaffold and Cytotoxicity Studies on CML Cell Lines Sensitive and Resistant to Imatinib
Pharmaceuticals·2025· 1 citedOpen Access
An Efficient and Selective 7-(Diethylamino)quinolin-2(1<i>H</i>)-One-Chalcone Fluorescent Probe for Detecting Bisulfite in Wine Samples Using a Micellar Solution
ACS Omega·2025· 1 citedOpen Access
First in class pyrrolo[2,3‐<i>d</i>]pyrimidine derivatives fused to fluorobenzylpiperidines as dual ligands of acetylcholinesterase and histamine H<sub>3</sub> receptor
Archiv der Pharmazie·2025· 2 citedOpen Access
Synthesis, antitumoral activity, and in silico studies on Smoothened receptor of new 2,6,9-trisubstituted purine derivatives
Journal of Molecular Structure·2025· 2 cited
Comparative Study of Phenolic Content and Antioxidant and Hepatoprotective Activities of Unifloral Quillay Tree (Quillaja saponaria Molina) and Multifloral Honeys from Chile
Plants·2024· 1 citedOpen Access
First Report on Cationic Triphenylphosphonium Compounds as Mitochondriotropic H3R Ligands with Antioxidant Properties
Antioxidants·2024Open Access
New Smoothened ligands based on the purine scaffold as potential agents for treating pancreatic cancer
Bioorganic Chemistry·2024· 3 cited
New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs
Pharmaceutics·2024· 3 citedOpen Access
Photoaged polystyrene nanoplastics exposure results in reproductive toxicity due to oxidative damage in Caenorhabditis elegans
Environmental Pollution·2024· 9 cited
Electrochemical oxidation of chlorpromazine, characterisation of products by mass spectroscopy and determination in pharmaceutical samples
Electrochimica Acta·2023· 22 cited
2,3-Diketopiperazine as potential scaffold to develop new anti-Chagasic agents
Medicinal Chemistry Research·2022· 1 cited
Development of 3D-QSAR and pharmacophoric models to design new anti-<i>Trypanosoma cruzi</i> agents based on 2-aryloxynaphthoquinone scaffold
SAR and QSAR in environmental research·2022· 5 cited
Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia
Pharmaceutics·2022· 10 citedOpen Access
New Amino Naphthoquinone Derivatives as Anti-Trypanosoma cruzi Agents Targeting Trypanothione Reductase
Pharmaceutics·2022· 18 citedOpen Access
Substituted Purines as High-Affinity Histamine H3 Receptor Ligands
Pharmaceuticals·2022· 5 citedOpen Access
Solvent‐Free Synthesis of New Quinoline Derivatives <i>via</i> Eaton's Reagent Catalysed Friedländer Synthesis
ChemistrySelect·2022· 13 cited
Expanding the chemical space of aryloxy-naphthoquinones as potential anti-Chagasic agents: synthesis and trypanosomicidal activity
Medicinal Chemistry Research·2021· 8 cited
Convergent synthesis, drug target prediction, and docking studies of new 2,6,9‐trisubstituted purine derivatives
Journal of Heterocyclic Chemistry·2021· 5 citedOpen Access
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Frequent Co-authors

Cristian O. Salas(33), Jaime Mella(14), Ricardo A. Tapia(9), Mario Faúndez(9), Margot Paulino(8), Adam Aguirre(7), Ana Marı́a Zarate(7), Alan R. Cabrera(7), Alejandro Castro‐Álvarez(7), C. David Pessoa‐Mahana(7), Karina Vázquez(5), Vladimı́r Kryštof(5), Jeanluc Bertrand(5), Angélica Fierro(4), Hugo Cerecetto(4), Radek Jorda(4), Gonzalo Recabarren‐Gajardo(4), Hernán Pessoa‐Mahana(4), Holger Stark(4), Gildardo Rivera(4)