Tad Guszczynski

Target (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index1.6kcitations20works0.02yr avg
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Research Topics

RNA modifications and cancer(5), Genomics and Chromatin Dynamics(3), Epigenetics and DNA Methylation(3), RNA and protein synthesis mechanisms(3), Cancer-related gene regulation(3)

Publications20 total

Isolation and structure elucidation of Dm-CVNH, a new cyanovirin-N homolog with activity against SARS-CoV-2 and HIV-1
Journal of Biological Chemistry·2025Open Access
Recifin A, Initial Example of the Tyr-Lock Peptide Structural Family, Is a Selective Allosteric Inhibitor of Tyrosyl-DNA Phosphodiesterase I
Journal of the American Chemical Society·2020· 17 citedOpen Access
IL-7-induced phosphorylation of the adaptor Crk-like and other targets
Cellular Signalling·2018· 8 citedOpen Access
Discovery and Characterization of a Biologically Active Non–ATP-Competitive p38 MAP Kinase Inhibitor
SLAS DISCOVERY·2015· 8 citedOpen Access
RSK-Mediated Phosphorylation in the C/EBPβ Leucine Zipper Regulates DNA Binding, Dimerization, and Growth Arrest Activity
Molecular and Cellular Biology·2010· 80 citedOpen Access
Activityand Growth Arrest Regulates DNA Binding, the C/EBP{beta} Leucine Zipper RSK-Mediated Phosphorylation in
2010
Interleukin-7 Regulates Bim Proapoptotic Activity in Peripheral T-Cell Survival
Molecular and Cellular Biology·2009· 32 citedOpen Access
Label-free global serum proteomic profiling reveals novel celecoxib-modulated proteins in familial adenomatous polyposis patients.
PubMed·2009· 18 cited
262 Development and maintenance of T-cell requires post-translational regulation of anti-apoptotic MCL-1 and pro-apoptotic BIM by IL-7
Cytokine·2008
IL-6 enhances the nuclear translocation of DNA cytosine-5-methyltransferase 1 (DNMT1) via phosphorylation of the nuclear localization sequence by the AKT kinase.
PubMed·2008· 109 cited
Cyclin-Dependent Kinase 5 Phosphorylation of Human Septin SEPT5 (hCDCrel-1) Modulates Exocytosis
Journal of Neuroscience·2008· 79 citedOpen Access
Interleukin (IL)‐7 inactivates pro‐apoptotic protein Bim at the posttranslational level in association with peripheral T‐cell survival
The FASEB Journal·2008
PTIP Associates with MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase Complex
Journal of Biological Chemistry·2007· 521 citedOpen Access
Mapping interactions of HIV‐1 Reverse Transcriptase with ligands by Protein Footprinting using chemical proteases
The FASEB Journal·2007
A microtiter plate fraction collector for the sequencing of radioactive phosphorylated peptides
Analytical Biochemistry·2006· 3 cited
Structure and activity of the atypical serine kinase Rio1
FEBS Journal·2005· 68 citedOpen Access
Autophosphorylation of <i>Archaeoglobus fulgidus</i> Rio2 and crystal structures of its nucleotide–metal ion complexes
FEBS Journal·2005· 44 citedOpen Access
Alternative p38 activation pathway mediated by T cell receptor–proximal tyrosine kinases
Nature Immunology·2005· 297 cited
The Parafibromin Tumor Suppressor Protein Is Part of a Human Paf1 Complex
Molecular and Cellular Biology·2005· 280 citedOpen Access
A Binding Shift Assay for the Zinc-Bound and Zinc-Free HIV-1 Nucleocapsid Protein by Capillary Electrophoresis
Analytical Biochemistry·1998· 28 cited

Frequent Co-authors

Terry D. Copeland(7), Scott K. Durum(4), Wenqing Li(3), Julie A. Hixon(3), Barry R. O’Keefe(3), Jonathan D. Ashwell(2), Sook Lee(2), Jon D. Shuman(2), Zhen Xiao(2), Timothy D. Veenstra(2), N. LaRonde-LeBlanc(2), Terry Copeland(2), Alexander Wlodawer(2), Lauren R. H. Krumpe(2), Brice A. P. Wilson(2), Shilpa R. Shenoy(2), Young‐Wook Cho(1), Teresa Hong(1), SunHwa Hong(1), Hong Guo(1)