Arne Holmgren

Karolinska Institutet — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

123h-index56.3kcitations459works0.02yr avg
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Research Topics

Redox biology and oxidative stress(369), Glutathione Transferases and Polymorphisms(116), Sulfur Compounds in Biology(98), Selenium in Biological Systems(63), Endoplasmic Reticulum Stress and Disease(57)

Publications459 total

Migratory behavior and maternal origin of anadromous brown trout in the Baltic Sea
Marine Ecology Progress Series·2023· 1 cited
Parkin coregulates glutathione metabolism in adult mammalian brain
Acta Neuropathologica Communications·2023· 13 citedOpen Access
Photoreceptor laminin drives differentiation of human pluripotent stem cells to photoreceptor progenitors that partially restore retina function
Molecular Therapy·2023· 12 citedOpen Access
Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice
Redox Biology·2022· 29 citedOpen Access
A substitution in the glutathione reductase lowers electron leakage and inflammation in modern humans
Science Advances·2022· 16 citedOpen Access
Analysis of glutathione mediated S-(de)nitrosylation in complex biological matrices by immuno-spin trapping and identification of two novel substrates
Nitric Oxide·2021· 11 citedOpen Access
Ribonucleotide reductase: In-vitro S-glutathionylation of R2 and p53R2 subunits of mammalian class I ribonucleotide reductase protein
Molecular Biology Reports·2021· 3 cited
Ribonucleotide Reductase: In-vitro S-glutathionylation of R2 and p53R2 Subunits of Mammalian Class I Ribonucleotide Reductase Protein
2021Open Access
CCDC 2056333: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
Metallocenyl derivatives of ebselen are selective and competitive inhibitors of thioredoxin reductase
Journal of Organometallic Chemistry·2021· 6 cited
CCDC 2056334: Experimental Crystal Structure Determination
The Cambridge Structural Database·2021Open Access
Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites
Acta Neuropathologica·2021· 56 citedOpen Access
S‐Denitrosylation by the C‐Terminal Swinging Arm of R1 Subunit: A Novel Mechanism to Restore Ribonucleotide Reductase Activity
ChemistrySelect·2021· 5 cited
Age-Associated Insolubility of Parkin in Human Midbrain is Linked to Redox Balance and Sequestration of Reactive Dopamine Metabolites
2020· 5 citedOpen Access
Inhibition of Thioredoxin Reductase by Triosmium Carbonyl Clusters
Chemical Research in Toxicology·2020· 8 cited
Selenium Status in Diet Affects Acetaminophen-Induced Hepatotoxicity <i>via</i> Interruption of Redox Environment
Antioxidants and Redox Signaling·2020· 16 citedOpen Access
Parkinson Disease-Linked Parkin Mediates Redox Reactions That Lower Oxidative Stress In Mammalian Brain
2020· 7 citedOpen Access
Inhibition of thioredoxin reductase 1 correlates with platinum-based chemotherapeutic induced tissue injury
Biochemical Pharmacology·2020· 24 cited
Oxidative Modifications of Parkin Underlie its Selective Neuroprotection in Adult Human Brain
2020· 2 citedOpen Access
Topical Therapeutic Efficacy of Ebselen Against Multidrug-Resistant Staphylococcus aureus LT-1 Targeting Thioredoxin Reductase
Frontiers in Microbiology·2020· 51 citedOpen Access
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Frequent Co-authors

Jun Lu(10), Christopher Horst Lillig(7), Elias S.J. Arnér(5), Carsten Berndt(5), Liangwei Zhong(4), C. Johansson(4), Laura V. Papp(3), Mikael Björnstedt(3), Fredrik Åslund(3), Maria Lönn(3), Christoph Hudemann(3), Kum Kum Khanna(2), Jianguo Fang(2), Eng‐Hui Chew(2), Cristina Carvalho(2), Jiyan Xue(2), Pietro Ghezzi(2), Michael P. Murphy(1), Nils‐Göran Larsson(1), Barry Halliwell(1)