Paolo Puccetti

University of Perugia — Italy

Neuroscience · Life Sciences

88h-index28.0kcitations355works12.52yr avg
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Research Topics

Tryptophan and brain disorders(73), Immunotherapy and Immune Responses(72), Immune Cell Function and Interaction(68), Antifungal resistance and susceptibility(64), T-cell and B-cell Immunology(57)

Publications355 total

Host–microbe serotonin metabolism
Trends in Endocrinology and Metabolism·2024· 31 citedOpen Access
Phenotypic drug discovery: a case for thymosin alpha-1
Frontiers in Medicine·2024· 2 citedOpen Access
A microbially produced AhR ligand promotes a Tph1-driven tolerogenic program in multiple sclerosis
Scientific Reports·2024· 17 citedOpen Access
SARS-CoV-2 Infection is Associated with Age- and Gender-Specific Changes in the Nasopharyngeal Microbiome
Frontiers in Bioscience-Landmark·2024Open Access
Host-microbe tryptophan partitioning in cardiovascular diseases
Pharmacological Research·2023· 4 citedOpen Access
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Protein S1 Induces Methylglyoxal-Derived Hydroimidazolone/Receptor for Advanced Glycation End Products (MG-H1/RAGE) Activation to Promote Inflammation in Human Bronchial BEAS-2B Cells
International Journal of Molecular Sciences·2023· 6 citedOpen Access
SARS-CoV-2 Spike Protein S1 Induces MG-H1/RAGE Activation to Promote Inflammation in Human Bronchial BEAS-2B Cells
Preprints.org·2023· 1 citedOpen Access
A tryptophan metabolite prevents depletion of circulating endothelial progenitor cells in systemic low-grade inflammation
Frontiers in Immunology·2023· 5 citedOpen Access
Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication
Immunity·2022· 106 citedOpen Access
T cell fat catabolism: A novel target for kynurenine?
EBioMedicine·2021· 3 citedOpen Access
Tryptophan Metabolites at the Crossroad of Immune-Cell Interaction via the Aryl Hydrocarbon Receptor: Implications for Tumor Immunotherapy
International Journal of Molecular Sciences·2021· 54 citedOpen Access
Novel mutations in the <i>WFS1</i> gene are associated with Wolfram syndrome and systemic inflammation
Human Molecular Genetics·2021· 33 citedOpen Access
Aspergillus fumigatus tryptophan metabolic route differently affects host immunity
Cell Reports·2021· 34 citedOpen Access
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1
EMBO Reports·2020· 43 citedOpen Access
Reply to Han et al.: On track for an IDO1-based personalized therapy in autoimmunity
Proceedings of the National Academy of Sciences·2020· 2 citedOpen Access
Off-label therapy targeting pathogenic inflammation in COVID-19
Cell Death Discovery·2020· 25 citedOpen Access
Pharmacologic Induction of Endotoxin Tolerance in Dendritic Cells by L-Kynurenine
Frontiers in Immunology·2020· 35 citedOpen Access
Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation
Proceedings of the National Academy of Sciences·2020· 80 citedOpen Access
HOPS/TMUB1 retains p53 in the cytoplasm and sustains p53‐dependent mitochondrial apoptosis
EMBO Reports·2019· 29 citedOpen Access
Engagement of Nuclear Coactivator 7 by 3-Hydroxyanthranilic Acid Enhances Activation of Aryl Hydrocarbon Receptor in Immunoregulatory Dendritic Cells
Frontiers in Immunology·2019· 71 citedOpen Access
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Frequent Co-authors

Francesca Fallarino(28), Ursula Grohmann(23), Carmine Vacca(23), Luigina Romani(21), Roberta Bianchi(19), Ciriana Orabona(18), Maria Laura Belladonna(16), Francesco Bistoni(16), Maria C. Fioretti(14), Claudia Volpi(10), Teresa Zelante(8), Silvia Bozza(7), Antonella Mencacci(7), Elio Cenci(7), Maria Cristina Fioretti(6), Claudia Montagnoli(6), Antonella De Luca(5), Maria Teresa Pallotta(5), Silvio Bicciato(5), Louis Boon(5)