John J. LaFrancois

Nathan Kline Institute for Psychiatric Research — United States

Neuroscience · Life Sciences

25h-index5.6kcitations63works0.92yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(29), Alzheimer's disease research and treatments(20), Neurogenesis and neuroplasticity mechanisms(18), Neurological Disorders and Treatments(11), Memory and Neural Mechanisms(8)

Publications63 total

Chemogenetic activation of hippocampal area CA2 promotes acute and chronic seizures in a mouse model of epilepsy
Neurobiology of Disease·2026Open Access
Chemogenetic activation of hippocampal area CA2 promotes acute and chronic seizures in a mouse model of epilepsy
2025Open Access
Testosterone and 17β-estradiol regulate hippocampal area CA3 sharp waves in male and female rats
Cell Reports·2025Open Access
Evidence that cholinergic mechanisms contribute to hyperexcitability at early stages in Alzheimer’s disease
Frontiers in Dementia·2025Open Access
Field <scp>EPSPs</scp> of Dentate Gyrus Granule Cells Studied by Selective Optogenetic Activation of Hilar Mossy Cells in Hippocampal Slices
Hippocampus·2024· 2 citedOpen Access
Field EPSPs of dentate gyrus granule cells studied by selective optogenetic activation of hilar mossy cells in hippocampal slices
2024Open Access
Author response: Increasing adult-born neurons protects mice from epilepsy
2024Open Access
Increasing adult-born neurons protects mice from epilepsy
eLife·2024· 2 citedOpen Access
Author response: Increasing adult neurogenesis protects mice from epilepsy
2024Open Access
Increasing adult neurogenesis protects mice from epilepsy
2024Open Access
Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease
eLife·2024· 6 citedOpen Access
Author response: Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease
2024Open Access
Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease
2024Open Access
Author response: Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease
2024Open Access
Joint Public Review: Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease
2024Open Access
Author response: Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease
2024Open Access
Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease
2024· 1 citedOpen Access
Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer’s disease
eLife·2024· 5 citedOpen Access
Reviewer #2 (Public Review): Increasing adult neurogenesis protects mice from epilepsy
2023Open Access
Increasing adult-born neurons protects mice from epilepsy
eLife·2023· 5 citedOpen Access
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Frequent Co-authors

Helen E. Scharfman(30), Justin J. Botterill(19), Swati Jain(19), Karen Duff(16), Kasey Gerencer(12), Paige Leary(11), David Alcantara‐Gonzalez(9), Yasuji Matsuoka(8), Elissavet Chartampila(6), Karim S. Elayouby(6), Stephen D. Ginsberg(6), Meghan Kennedy(6), Lorenzo M. Refolo(5), Brian Malester(5), Wendy Noble(5), Vicki Olm(5), Kate Gaynor(5), Chiara Criscuolo(5), Miguel A. Pappolla(4), Mark P. Burns(4)