Rohit Kolhatkar

United States Food and Drug Administration — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index1.4kcitations26works0.52yr avg
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Research Topics

RNA Interference and Gene Delivery(12), Dendrimers and Hyperbranched Polymers(9), Advanced biosensing and bioanalysis techniques(6), Neurotransmitter Receptor Influence on Behavior(5), Neuroscience and Neuropharmacology Research(5)

Publications26 total

US Food and Drug Administration Approval Summary: Ribociclib With an Aromatase Inhibitor in the Adjuvant Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Stage II and III High-Risk Early Breast Cancer Treatment Setting
Journal of Clinical Oncology·2025· 1 cited
The Role of Enhanced Analytical Procedure Development in Facilitating Post-Approval Changes Via Established Conditions
The AAPS Journal·2025Open Access
Delivery of HSP90 Inhibitor Using Water Soluble Polymeric Conjugates with High Drug Payload
Pharmaceutical Research·2017· 2 cited
Dendritic hexadecapeptide as a cathepsin B degradable carrier for delivery of HSP90 inhibitor
Bioorganic & Medicinal Chemistry Letters·2015· 4 cited
Oligospermines and Nucleic Acid Interaction: A Structure Property Relationship Study
ACS Macro Letters·2014· 5 cited
Star-Shaped Tetraspermine Enhances Cellular Uptake and Cytotoxicity of T-Oligo in Prostate Cancer Cells
Pharmaceutical Research·2014· 7 cited
Influence of Oligospermines Architecture on Their Suitability for siRNA Delivery
Biomacromolecules·2014· 32 citedOpen Access
Cathepsin B Degradable Star-Shaped Peptidic Macromolecules for Delivery of 2-Methoxyestradiol
Molecular Pharmaceutics·2013· 30 cited
Active Tumor Targeting of Nanomaterials Using Folic Acid, Transferrin and Integrin Receptors
Current Drug Discovery Technologies·2011· 60 cited
Complexes of Bacterial Nicotinate Mononucleotide Adenylyltransferase with Inhibitors: Implication for Structure-Based Drug Design and Improvement
Journal of Medicinal Chemistry·2010· 27 citedOpen Access
Transepithelial transport of PEGylated anionic poly(amidoamine) dendrimers: Implications for oral drug delivery
Journal of Controlled Release·2009· 93 citedOpen Access
Targetable HPMA Copolymer–Aminohexylgeldanamycin Conjugates for Prostate Cancer Therapy
Pharmaceutical Research·2009· 44 citedOpen Access
Tumor-targeted HPMA copolymer-(RGDfK)-(CHX-A″-DTPA) conjugates show increased kidney accumulation
Journal of Controlled Release·2008· 56 citedOpen Access
Potential Oral Delivery of 7-Ethyl-10-Hydroxy-Camptothecin (SN-38) using Poly(amidoamine) Dendrimers
Pharmaceutical Research·2008· 99 citedOpen Access
Further structural optimization of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine and 1,4-diazabicyclo[3.3.1]nonane derivatives by introducing an exocyclic hydroxyl group: Interaction with dopamine, serotonin, and norepinephrine transporters
Bioorganic & Medicinal Chemistry·2008· 9 citedOpen Access
Endocytosis Inhibitors Prevent Poly(amidoamine) Dendrimer Internalization and Permeability across Caco-2 Cells
Molecular Pharmaceutics·2008· 154 cited
Functionalized Dendrimers as Nanoscale Drug Carriers
Fundamental biomedical technologies·2008· 10 cited
Surface Acetylation of Polyamidoamine (PAMAM) Dendrimers Decreases Cytotoxicity while Maintaining Membrane Permeability
Bioconjugate Chemistry·2007· 286 cited
Endocytosis and Interaction of Poly (Amidoamine) Dendrimers with Caco-2 Cells
Pharmaceutical Research·2007· 181 cited
Mazindol
xPharm: The Comprehensive Pharmacology Reference·2007
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Frequent Co-authors

Hamidreza Ghandehari(9), Peter W. Swaan(6), Aloke K. Dutta(6), Maarten E. A. Reith(6), Kelly M. Kitchens(4), Vidula Kolhatkar(4), Asawari R. Lote(3), D. Sweet(2), Abhijit Ray(2), Mark P. Borgman(2), Sujit K. Ghorai(2), Patrick M. Beardsley(2), Thomas Insley(2), Petr Král(2), Amy B. Foraker(1), Natalie D. Eddington(1), Shijun Zhang(1), Hiren Khambhati(1), Tomika Coleman(1), Sandra Geyser-Stoops(1)