Rosa Bacchetta

Lucile Packard Children's Hospital — United States

Immunology and Microbiology · Life Sciences

61h-index16.1kcitations212works1.32yr avg
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Research Topics

Immune Cell Function and Interaction(129), T-cell and B-cell Immunology(113), Immunodeficiency and Autoimmune Disorders(43), CAR-T cell therapy research(31), Immunotherapy and Immune Responses(27)

Publications212 total

T-allo10 Cell Addback Post-Αβdepleted-HSCT Drives Lasting Leukemia-Free Survival with Distinct Immune Regulation Biomarkers
Transplantation and Cellular Therapy·2026
Genetic testing guides therapy in children with refractory cytopenias
Haematologica·2026Open Access
IL10 gene mutations do not impair Tr1 differentiation in vivo and can be functionally corrected by precise gene editing 9296
The Journal of Immunology·2025Open Access
Regulatory T cell therapies: from patient data to biological insights
Frontiers in Immunology·2025· 1 citedOpen Access
CXCR6⁺ CD127⁻ Tr1 Cells Balance Immunity and Persistence in Plasmodium falciparum Infection
2025Open Access
Autologous Lentiviral Vector LVFOXP3 CD4 T Cells for IPEX Syndrome
Journal of Human Immunity·2025Open Access
Patients with Genetic Immune Diseases in the Hematologist’s Waiting Room
Journal of Human Immunity·2025Open Access
Clone tracking through repeated malaria identifies high-fidelity memory CD4 T cell responses
Science Immunology·2025· 4 cited
Editorial: Inborn Errors of Immunity (IEI) breaking immune homeostasis and tolerance: a key role for T regulatory cells
Frontiers in Immunology·2024Open Access
Immune Dysregulation Polyendocrinopathy Enteropathy X-Linked Syndrome
Elsevier eBooks·2024
Regulatory T Cell (Treg) Characterization
2024· 1 citedOpen Access
T-allo10 Immunotherapy Results in Enhanced Early Immune Reconstitution and Reduced GvHD with Excellent Clinical Outcomes Post Αβ-Depleted HSCT in Pediatric and Young Adult Hematologic Malignancy Patients
Blood·2024Open Access
AML/T cell interactomics uncover correlates of patient outcomes and the key role of ICAM1 in T cell killing of AML
Leukemia·2024· 12 citedOpen Access
96 Molecular and functional identification of unstable regulatory and autoreactive effector T cells that are expanded in patients with FOXP3 mutation
Clinical Immunology·2024
Epigenetic signature and key transcriptional regulators of human antigen-specific type 1 regulatory T cells
2024· 1 citedOpen Access
A novel FOXP3 knockout-humanized mouse model for pre-clinical safety and efficacy evaluation of Treg-like cell products
Molecular Therapy — Methods & Clinical Development·2024Open Access
A multidisciplinary approach to unraveling genetic forms of immune dysregulation in children with refractory multilineage cytopenia
Journal of Allergy and Clinical Immunology·2024Open Access
Enhanced Immune Reconstitution and Reduced GvHD Risk with T-allo10 Infusion Post Aβdepleted-HSCT in Pediatric and Young Adult Patients with Hematologic Malignancies
Transplantation and Cellular Therapy·2024
Case report: Refractory Evans syndrome in two patients with spondyloenchondrodysplasia with immune dysregulation treated successfully with JAK1/JAK2 inhibition
Frontiers in Immunology·2024· 8 citedOpen Access
Interleukin-2 Receptor Alpha Chain (CD25) Deficiency
2024
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Frequent Co-authors

Maria Grazia Roncarolo(19), Silvia Gregori(12), Megan K. Levings(9), Laura Passerini(9), Manuela Battaglia(6), Maria-Grazia Roncarolo(6), Maria‐Grazia Roncarolo(6), Federica Barzaghi(5), Eleonora Gambineri(5), J E de Vries(4), Caterina Cancrini(4), Fabio Ciceri(4), Claudio Bordignon(3), Mike Bigler(3), Andrew R. Gennery(3), Alessandro Plebani(3), Claudio Pignata(3), Alessandro Aiuti(3), Barbarella Lucarelli(3), Silvana Martino(3)