Luisa Mosti

University of Milan — Italy

Chemistry · Physical Sciences

27h-index2.3kcitations188works0.02yr avg
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Research Topics

Synthesis and Reactions of Organic Compounds(63), Synthesis of heterocyclic compounds(46), Synthesis and biological activity(45), Synthesis and Biological Evaluation(39), Synthesis and Characterization of Heterocyclic Compounds(29)

Publications188 total

Synthesis and Preliminary Biological Evaluation of Novel N-Substituted 1-Amino-3-[1-methyl(phenyl)-1H-indazol-4-yloxy]-propan-2-ols Interesting as Potential Antiarrhythmic, Local Anaesthetic and Analgesic Agents
Arzneimittelforschung·2011· 18 cited
CoMFA and CoMSIA analyses on 1,2,3,4-tetrahydropyrrolo[3,4-b]indole and benzimidazole derivatives as selective CB2 receptor agonists
Journal of Molecular Modeling·2010· 29 citedOpen Access
CoMFA and CoMSIA analyses on 4-oxo-1,4-dihydroquinoline and 4-oxo-1,4-dihydro-1,5-, -1,6- and -1,8-naphthyridine derivatives as selective CB2 receptor agonists
Journal of Molecular Modeling·2009· 15 cited
The XIXth National Meeting on Medicinal Chemistry: Verona, Italy
ChemMedChem·2009Open Access
Exploring the QSAR of Pyrazolo[3,4‐<i>b</i>]Pyridine, Pyrazolo[3,4‐<i>b</i>]Pyridone and Pyrazolo[3,4‐<i>b</i>]Pyrimidine Derivatives as Antagonists for A<sub>1</sub> Adenosine Receptor
QSAR & Combinatorial Science·2009· 4 cited
Acylthiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: docking studies and ligand-based CoMFA and CoMSIA analyses
Journal of Molecular Modeling·2009· 19 cited
Computational studies of the binding mode and 3D-QSAR analyses of symmetric formimidoester disulfides: a new class of non-nucleoside HIV-1 reverse transcriptase inhibitor
Journal of Molecular Modeling·2008· 7 cited
Thiocarbamates as non-nucleoside HIV-1 reverse transcriptase inhibitors: Docking-based CoMFA and CoMSIA analyses
European Journal of Medicinal Chemistry·2008· 26 cited
Exploring the binding features of rimonabant analogues and acyclic CB1 antagonists: docking studies and QSAR analysis
Journal of Molecular Modeling·2008· 13 cited
Substituted Pyrazolo[3,4‐<i>b</i>]pyridines as Potent A<sub>1</sub> Adenosine Antagonists: Synthesis, Biological Evaluation, and Development of an A<sub>1</sub> Bovine Receptor Model
ChemMedChem·2008· 24 cited
Quinolinedione nucleus as a novel scaffold for A1 and A2A adenosine receptor antagonists
Medicinal Chemistry Research·2008· 2 cited
Rational design, synthesis and biological evaluation of new 1,5-diarylpyrazole derivatives as CB1 receptor antagonists, structurally related to rimonabant
European Journal of Medicinal Chemistry·2008· 27 citedOpen Access
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines
European Journal of Medicinal Chemistry·2008· 74 citedOpen Access
New pyrazolo 3,4-bpyridines antagonists of A1 adenosine receptors
CINECA IRIS Institutial research information system (University of Pisa)·2008
Synthesis of indole imminun salts as key-intermediates in a convergent multi-step one-pot stereoselective synthesis of new potent antiproliferative Knoevenagel-type agent
2008
Unprecedented One‐Pot Stereoselective Synthesis of Knoevenagel‐Type Derivatives via in situ Condensation of N‐Methyleniminium Salts of Ethylenethiourea and Ethyleneurea with Active Methylene Reagents.
ChemInform·2007
Unprecedented One-Pot Stereoselective Synthesis of Knoevenagel-Type Derivatives via in situ Condensation of <i>N</i>-Methyleniminium Salts of Ethylenethiourea and Ethyleneurea with Active Methylene Reagents
Synthesis·2007· 9 cited
Synthesis and In Vitro Antiplatelet Activity of New 4-(1-Piperazinyl)coumarin Derivatives. Human Platelet Phosphodiesterase 3 Inhibitory Properties of the Two Most Effective Compounds Described and Molecular Modeling Study on Their Interactions with Phosphodiesterase 3A Catalytic Site
Journal of Medicinal Chemistry·2007· 38 citedOpen Access
Pyrazolo[3,4-<i>d</i>]pyrimidines as Potent Antiproliferative and Proapoptotic Agents toward A431 and 8701-BC Cells in Culture via Inhibition of c-Src Phosphorylation
Journal of Medicinal Chemistry·2006· 87 citedOpen Access
Synthesis of pyrazolo[3,4-d]pyridines selective antagonists of A1 adenosine receptors
CINECA IRIS Institutial Research Information System (University of Genoa)·2006
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Frequent Co-authors

Giulia Menozzi(33), Paola Fossa(29), P. SCHENONE(15), Silvia Schenone(13), Francesco Bondavalli(13), Olga Bruno(12), Angelo Ranise(12), Fabrizio Manetti(9), Maurizio Botta(8), P. Dorigo(7), Chiara Brullo(6), Maria Letizia Trincavelli(5), Claudia Martini(5), Andrea Spallarossa(5), Sara Cesarini(5), Elena Cichero(5), Francesca Mattioli(4), Fabio Carraro(4), Cristina Tintori(4), Antonella Naldini(3)