Massimo Gadina

National Institute of Arthritis and Musculoskeletal and Skin Diseases — United States

Medicine · Health Sciences

70h-index27.3kcitations202works11.62yr avg
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Research Topics

Cytokine Signaling Pathways and Interactions(70), Immune Cell Function and Interaction(42), Inflammasome and immune disorders(29), T-cell and B-cell Immunology(24), interferon and immune responses(20)

Publications201 total

Type I interferon signature associates with lung disease, drug‐associated immune reactions, and genetic variation in interferon‐linked pathways in Still's disease
Arthritis & Rheumatology·2026
Epigenetic dysregulation in aged muscle stem cells drives mesenchymal progenitor expansion via IL-6 and Spp1 signaling
Nature Aging·2025· 5 citedOpen Access
Type I interferon-mediated autoinflammation in two unrelated patients due to a proximal intronic splice site variant in DNASE2
2025Open Access
HMGCS1 Deficiency Is a Novel Immunometabolic Autoinflammatory Disease with Progressive Myositis
Journal of Human Immunity·2025Open Access
A coding single nucleotide polymorphism in the interleukin-6 receptor enhances IL-6 signalling in CD4 T cells and predicts treatment response to tocilizumab in giant cell arteritis
Annals of the Rheumatic Diseases·2025· 7 citedOpen Access
Next generation sequencing analysis reveals complex genetic architecture of childhood-onset systemic lupus erythematosus
Lupus Science & Medicine·2025· 3 citedOpen Access
JAK inhibitor selectivity: new opportunities, better drugs?
Nature Reviews Rheumatology·2024· 60 cited
A Multiomic Analysis to Identify Drivers of Subclinical Vascular Disease in Systemic Lupus Erythematosus
Arthritis & Rheumatology·2024· 5 citedOpen Access
JAKing up immunity
Science·2024· 7 cited
Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency
Nature Immunology·2024· 27 citedOpen Access
Interrupting an IFN-γ-dependent feedback loop in the syndrome of pyogenic arthritis with pyoderma gangrenosum and acne
Annals of the Rheumatic Diseases·2024· 14 citedOpen Access
Identification of Fibroinflammatory and Fibrotic Transcriptomic Subsets of Human Cutaneous Sclerotic Chronic Graft-Versus-Host Disease
JID Innovations·2023· 4 citedOpen Access
Clonal haematopoiesis across the age spectrum of vasculitis patients with Takayasu’s arteritis, ANCA-associated vasculitis and giant cell arteritis
Annals of the Rheumatic Diseases·2023· 23 citedOpen Access
Author Correction: Protein kinases: drug targets for immunological disorders
Nature reviews. Immunology·2023· 2 citedOpen Access
JAK inhibitors: Is specificity at all relevant?
Seminars in Arthritis and Rheumatism·2023· 9 citedOpen Access
Selectivity, efficacy and safety of JAKinibs: new evidence for a still evolving story
Annals of the Rheumatic Diseases·2023· 122 citedOpen Access
Divergent roles for STAT4 in shaping differentiation of cytotoxic ILC1 and NK cells during gut inflammation
Proceedings of the National Academy of Sciences·2023· 12 citedOpen Access
Identification of Unique microRNA Profiles in Different Types of Idiopathic Inflammatory Myopathy
Cells·2023· 10 citedOpen Access
Variant <i>STAT4</i> and Response to Ruxolitinib in an Autoinflammatory Syndrome
New England Journal of Medicine·2023· 62 citedOpen Access
Protein kinases: drug targets for immunological disorders
Nature reviews. Immunology·2023· 91 citedOpen Access
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Frequent Co-authors

John J. O’Shea(26), Daniel L. Kastner(12), Wanxia Li Tsai(11), Daniella M. Schwartz(10), Ivona Aksentijevich(9), Deborah L. Stone(8), Raphaela Goldbach‐Mansky(8), Stephen R. Brooks(7), Amanda K. Ombrello(6), Elaine F. Remmers(6), David M. Frucht(5), Chyi‐Chia Richard Lee(5), Hanna Kim(5), Manfred Boehm(5), Yuka Kanno(5), Sarfaraz Hasni(5), Patrycja Hoffmann(5), Anne Jones(5), James C. Mullikin(5), Jae Jin Chae(5)