Abde M. Abukhdeir

Rush University Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index2.1kcitations60works17.72yr avg

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

PI3K/AKT/mTOR signaling in cancer(12), Advanced Breast Cancer Therapies(9), Ion channel regulation and function(7), Cancer Genomics and Diagnostics(7), HER2/EGFR in Cancer Research(6)

Publications60 total

Abstract 5987: Mutations in PIK3R1 activate multiple targetable pathways in triple-negative breast cancer

Cancer Research·2025

US Food and Drug Administration Approval Summary: Talazoparib in Combination With Enzalutamide for Treatment of Patients With Homologous Recombination Repair Gene-Mutated Metastatic Castration-Resistant Prostate Cancer

22 cited

Journal of Clinical Oncology·2024· 22 citedOpen Access

US Food and Drug Administration Approval Summary: Elacestrant for Estrogen Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative, ESR1-Mutated Advanced or Metastatic Breast Cancer

31 cited

Journal of Clinical Oncology·2024· 31 citedOpen Access

Comparative genomic analysis of PIK3R1-mutated and wild-type breast cancers

4 cited

Breast Cancer Research and Treatment·2023· 4 cited

FDA Approval Summary: Olaparib in Combination With Abiraterone for Treatment of Patients With BRCA-Mutated Metastatic Castration-Resistant Prostate Cancer

47 cited

Journal of Clinical Oncology·2023· 47 cited

Abstract 2248: Activity of targeted agents in PIK3R1 mutated patient-derived xenografts

1 cited

Cancer Research·2023· 1 cited

Data from Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras–Mediated Transformation

2023Open Access

Data from Single Copies of Mutant KRAS and Mutant PIK3CA Cooperate in Immortalized Human Epithelial Cells to Induce Tumor Formation

2023Open Access

Supplementary Table 1, Figures 1-4 from Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras–Mediated Transformation

2023Open Access

Supplementary Figure Legends 1-4 from Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras–Mediated Transformation

2023Open Access

Supplementary Figure Legends 1-4 from Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras–Mediated Transformation

2023Open Access

Data from Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras–Mediated Transformation

2023Open Access

Data from Single Copies of Mutant KRAS and Mutant PIK3CA Cooperate in Immortalized Human Epithelial Cells to Induce Tumor Formation

2023Open Access

Supplementary Figures 1 - 8 from Single Copies of Mutant KRAS and Mutant PIK3CA Cooperate in Immortalized Human Epithelial Cells to Induce Tumor Formation

2023Open Access

Supplementary Figures 1 - 8 from Single Copies of Mutant KRAS and Mutant PIK3CA Cooperate in Immortalized Human Epithelial Cells to Induce Tumor Formation

2023Open Access

Supplementary Table 1, Figures 1-4 from Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras–Mediated Transformation

2023Open Access

Abstract P3-08-04: The genomic and transcriptomic landscape of PIK3R1 mutated breast cancers

Cancer Research·2022

FDA Approval Summary: Capmatinib and Tepotinib for the Treatment of Metastatic NSCLC Harboring MET Exon 14 Skipping Mutations or Alterations

160 cited

Clinical Cancer Research·2021· 160 citedOpen Access

Binimetinib activity in PIK3R1-mutant patient-derived xenografts (PDX) implanted into immunodeficient mice.

2 cited

Journal of Clinical Oncology·2021· 2 cited

Abstract PS18-30: Loss of NF1 leads to rho GTPase activation and sensitivity to multiple agents in breast cancer

Cancer Research·2021

page 1 of 3Next →

Frequent Co-authors

Ben Ho Park(20), John P. Gustin(17), Josh Lauring(17), Joseph P. Garay(17), Hiroyuki Konishi(15), Bedri Karakas(13), Yuko Konishi(12), Kurtis E. Bachman(10), Melody Cobleigh(10), Morassa Mohseni(8), Michaela J. Higgins(7), Matthew S. Najor(7), Duarte Mota de Freitas(7), Grace M. Wang(6), Pedram Argani(6), Brian Blair(6), Brian T. Layden(6), David Cosgrove(5), Hong Yuen Wong(5), Justin Cidado(5)