Michael L.J. Ashford

University of Dundee — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

56h-index15.7kcitations187works0.82yr avg
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Research Topics

Ion channel regulation and function(71), Pancreatic function and diabetes(42), Neuroscience and Neuropharmacology Research(32), Regulation of Appetite and Obesity(32), Adipose Tissue and Metabolism(22)

Publications187 total

Impact of Oral Immunity on Neuroinflammation and Neurodegenerative Diseases
Advances in experimental medicine and biology·2025
Expression of Concern for Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction
Journal of Clinical Investigation·2025Open Access
Activation of the Nrf2 Pathway by Sulforaphane Improves Hypoglycaemia-Induced Cognitive Impairment in a Rodent Model of Type 1 Diabetes
Antioxidants·2025· 4 citedOpen Access
Correction: Chronic hyperglycaemia increases the vulnerability of the hippocampus to oxidative damage induced during post-hypoglycaemic hyperglycaemia in a mouse model of chemically induced type 1 diabetes
Diabetologia·2024Open Access
AMYLOID-BETA 40 ADVERSELY INFLUENCES LARGE ARTERY STIFFNESS AND CUTANEOUS MICROVASCULAR FUNCTION IN OLDER ADULTS WITH DIVERSE CARDIOVASCULAR RISK
Journal of Hypertension·2024
Metformin increases the uptake of glucose into the gut from the circulation in high-fat diet-fed male mice, which is enhanced by a reduction in whole-body Slc2a2 expression
Molecular Metabolism·2023· 14 citedOpen Access
Chronic hyperglycaemia increases the vulnerability of the hippocampus to oxidative damage induced during post-hypoglycaemic hyperglycaemia in a mouse model of chemically induced type 1 diabetes
Diabetologia·2023· 11 citedOpen Access
A multi-disciplinary commentary on preclinical research to investigate vascular contributions to dementia
Cerebral Circulation - Cognition and Behavior·2023· 8 citedOpen Access
Central deficiency of IL-6Ra in mice impairs glucose-stimulated insulin secretion
Molecular Metabolism·2022· 5 citedOpen Access
Identifying the beta-site amyloid precursor protein cleaving enzyme 1 interactome through the proximity-dependent biotin identification assay
Neuroscience Letters·2021· 3 citedOpen Access
Non-canonical Keap1-independent activation of Nrf2 in astrocytes by mild oxidative stress
Redox Biology·2021· 37 citedOpen Access
The genetic association of the transcription factor NPAT with glycemic response to metformin involves regulation of fuel selection
PLoS ONE·2021Open Access
Adipocyte integrin-linked kinase plays a key role in the development of diet-induced adipose insulin resistance in male mice
Molecular Metabolism·2021· 25 citedOpen Access
Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction
Journal of Clinical Investigation·2020· 51 citedOpen Access
CD44 contributes to hyaluronan-mediated insulin resistance in skeletal muscle of high-fat-fed C57BL/6 mice
American Journal of Physiology-Endocrinology and Metabolism·2019· 57 citedOpen Access
270-OR: Adipocyte Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Adipose Insulin Resistance
Diabetes·2019
Corrigendum to “The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling” [Metab Clin Exp 85 (2018) 59–75]
Metabolism·2019· 1 citedOpen Access
Calcium Channel CaV2.3 Subunits Regulate Hepatic Glucose Production by Modulating Leptin-Induced Excitation of Arcuate Pro-opiomelanocortin Neurons
Cell Reports·2018· 11 citedOpen Access
Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology
Clinical Science·2018· 64 citedOpen Access
The beta secretase BACE1 regulates the expression of insulin receptor in the liver
Nature Communications·2018· 72 citedOpen Access
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Frequent Co-authors

Paul J. Meakin(10), C. N. Hales(7), Mark A. Smith(6), Jenni Harvey(6), Albena T. Dinkova‐Kostova(4), Nicholas C. Sturgess(4), John D. Hayes(4), Paco S. Herson(4), Raheela Khan(4), Jennifer Gallagher(3), David Spanswick(3), Marc Claret(3), Rachel L. Batterham(3), Colin Selman(3), Agharul I. Choudhury(3), Melanie Clements(3), Hind Al‐Qassab(3), Gregory S. Barsh(3), Dominic J. Withers(3), Shirin Mirshamsi(3)