Stanley Z. Lam

Memorial Sloan Kettering Cancer Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index785citations18works21.42yr avg
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Research Topics

CRISPR and Genetic Engineering(10), CAR-T cell therapy research(9), Virus-based gene therapy research(4), Immune Cell Function and Interaction(4), T-cell and B-cell Immunology(3)

Publications18 total

Longitudinal and multisite sampling reveals mutational and copy number evolution in tumors during metastatic dissemination
Nature Genetics·2025· 3 citedOpen Access
Cas12a-knock-in mice for multiplexed genome editing, disease modelling and immune-cell engineering
Nature Biomedical Engineering·2025· 18 citedOpen Access
Prediction of checkpoint inhibitor immunotherapy efficacy for cancer using routine blood tests and clinical data
Nature Medicine·2025· 79 citedOpen Access
65 High-fidelity enhanced AsCas12a knock-in mice for efficient multiplexed gene editing, disease modeling and orthogonal immunogenetics
Regular and Young Investigator Award Abstracts·2024Open Access
In vivo AAV–SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy
Nature Biotechnology·2024· 42 cited
High-fidelity enhanced AsCas12a knock-in mice for efficient multiplexed gene editing, disease modeling and orthogonal immunogenetics
2024Open Access
A Culturally Specific Community Supported Agriculture (CSA) Program to Improve Diet in Immigrant Communities in Brooklyn, New York
Health Promotion Practice·2024· 8 citedOpen Access
AAV-mediated delivery of a Sleeping Beauty transposon and an mRNA-encoded transposase for the engineering of therapeutic immune cells
Nature Biomedical Engineering·2023· 27 citedOpen Access
Perturbomics of tumor-infiltrating NK cells
2023· 5 citedOpen Access
Therapeutic immune cell engineering with an mRNA : AAV- <i>Sleeping Beauty</i> composite system
2023· 2 citedOpen Access
Massively parallel knock-in engineering of human T cells
Nature Biotechnology·2023· 49 citedOpen Access
Machine learning identifies T cell receptor repertoire signatures associated with COVID-19 severity
Communications Biology·2023· 41 citedOpen Access
Double knockout CRISPR screen for cancer resistance to T cell cytotoxicity
Journal of Hematology & Oncology·2022· 13 citedOpen Access
Genome Engineering for Next-Generation Cellular Immunotherapies
Biochemistry·2022· 1 citedOpen Access
A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
Cell Metabolism·2022· 181 citedOpen Access
Double knockout CRISPR screen in cancer resistance to T cell cytotoxicity
2022· 4 citedOpen Access
T cell receptor repertoire signatures associated with COVID-19 severity
2021· 4 citedOpen Access
Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells
Cell·2019· 308 citedOpen Access

Frequent Co-authors

Sidi Chen(15), Jonathan J. Park(10), Ryan D. Chow(8), Lupeng Ye(8), Xiaoyu Zhou(6), Yueqi Zhang(6), Paul Clark(6), Matthew B. Dong(5), Lei Peng(5), Luojia Yang(5), Xiaoyun Dai(4), Paul Renauer(4), Johanna Shen(4), Hanbing Cao(4), Xin Shan(4), Qianqian Lin(4), Hyunu R. Kim(3), Yaying Du(3), Jianjian Guo(3), Yongji Zou(3)