Eric Oldfield

University of Illinois Urbana-Champaign — United States

Chemistry · Physical Sciences

94h-index31.7kcitations686works2.32yr avg
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Research Topics

Advanced NMR Techniques and Applications(143), Biochemical and Molecular Research(99), Plant biochemistry and biosynthesis(93), Enzyme Structure and Function(65), NMR spectroscopy and applications(64)

Publications686 total

Antifungal Activity of Lipophilic Bisphosphonates
ACS Infectious Diseases·2026
Activity of Antibacterial/Antifungal Compounds against the Protozoan Parasite, <i>Toxoplasma gondii</i>
ACS Infectious Diseases·2025· 1 cited
Broad-Spectrum Activity and Mechanisms of Action of SQ109 on a Variety of Fungi
ACS Infectious Diseases·2025· 3 cited
Anti-Parasitics with a Triple Threat: Targeting Parasite Enzymes, the Proton Motive Force, and Host Cell-Mediated Killing
ACS Infectious Diseases·2025· 1 cited
Activity of Carbazole, Aminoguanidine and Diamine Anti-infectives against <i>Toxoplasma gondii</i>
2025Open Access
Anti-Parasitics with a Triple Threat: Targeting Parasite Enzymes, the Proton Motive Force, and Host Cell-Mediated Killing
2025· 1 citedOpen Access
Broad-Spectrum Activity and Mechanisms of Action of SQ109 on a Variety of Fungi
2025Open Access
Lipophilic bisphosphonates reduced cyst burden and ameliorated hyperactivity of mice chronically infected with <i>Toxoplasma gondii</i>
mBio·2024· 7 citedOpen Access
The Tuberculosis Drug Candidate SQ109 and Its Analogs Have Multistage Activity against <i>Plasmodium falciparum</i>
ACS Infectious Diseases·2024· 8 citedOpen Access
Phosphoantigens glue butyrophilin 3A1 and 2A1 to activate Vγ9Vδ2 T cells
Nature·2023· 113 citedOpen Access
Investigation into the Mechanism of Action of the Tuberculosis Drug Candidate SQ109 and Its Metabolites and Analogues in Mycobacteria
Journal of Medicinal Chemistry·2023· 13 citedOpen Access
Distinct Energy-Coupling Factor Transporter Subunits Enable Flavin Acquisition and Extracytosolic Trafficking for Extracellular Electron Transfer in Listeria monocytogenes
mBio·2023· 18 citedOpen Access
Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against <i>Mycobacterium abscessus</i> and Malaria Parasites
ACS Infectious Diseases·2023· 19 citedOpen Access
Distinct energy-coupling factor transporter subunits enable flavin acquisition and extracytosolic trafficking for extracellular electron transfer in <i>Listeria monocytogenes</i>
2022· 1 citedOpen Access
Synthesis and Testing of Analogs of the Tuberculosis Drug SQ109 Against Bacteria and Protozoa: Identification of Lead Compounds Against Mycobacterium abscessus and Malaria
2022Open Access
The Heptaprenyl Diphosphate Synthase (Coq1) Is the Target of a Lipophilic Bisphosphonate That Protects Mice against Toxoplasma gondii Infection
mBio·2022· 15 citedOpen Access
A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins
ACS Omega·2022· 14 citedOpen Access
The heptaprenyl diphosphate synthase (Coq1) is the target of a lipophilic bisphosphonate that protects mice against <i>Toxoplasma gondii</i> infection
2022· 2 citedOpen Access
In Vivo Efficacy of SQ109 against Leishmania donovani, Trypanosoma spp. and Toxoplasma gondii and In Vitro Activity of SQ109 Metabolites
Biomedicines·2022· 11 citedOpen Access
Phosphoantigens are Molecular Glues that Promote Butyrophilin 3A1/2A1 Association Leading to Vγ9Vδ2 T Cell Activation
2022· 6 citedOpen Access
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Frequent Co-authors

Roberto Docampo(6), Yonghui Zhang(6), Julio A. Urbina(5), Michael Martin(4), Xinxin Feng(4), Rey‐Ting Guo(4), Yongcheng Song(3), Fenglin Yin(3), Andrew H.‐J. Wang(3), David M. Rice(3), Andrzej Więckowski(3), Jared C. Lewis(3), Brian N. Bailey(3), Gary L. Turner(3), Karen Smith(3), R. James Kirkpatrick(3), Rong Cao(3), M.P. Hudock(3), D. Chapman(2), W.Y. Jeng(2)