Jan Wehkamp

Janssen (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

58h-index14.6kcitations323works11.42yr avg
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Research Topics

Inflammatory Bowel Disease(120), Antimicrobial Peptides and Activities(106), Microscopic Colitis(70), Probiotics and Fermented Foods(41), Gut microbiota and health(40)

Publications321 total

Author Correction: Gut microbiota strain richness is species specific and affects engraftment
Nature·2025Open Access
Gut microbiota strain richness is species specific and affects engraftment
Nature·2024· 41 citedOpen Access
Age-related patterns of microbial dysbiosis in multiplex inflammatory bowel disease families
Gut·2024· 9 citedOpen Access
Host defense peptides human β defensin 2 and LL-37 ameliorate murine necrotizing enterocolitis
iScience·2024· 7 citedOpen Access
Host Defense Peptides Human β Defensin 2 and LL-37 Ameliorate Murine Necrotizing Enterocolitis
SSRN Electronic Journal·2024Open Access
Using Computer Vision to Improve Endoscopic Disease Quantification in Therapeutic Clinical Trials of Ulcerative Colitis
Gastroenterology·2023· 48 citedOpen Access
Human α-Defensin 51–9 and Human β-Defensin 2 Improve Metabolic Parameters and Gut Barrier Function in Mice Fed a Western-Style Diet
International Journal of Molecular Sciences·2023· 14 citedOpen Access
Mo1736 PREDICTING REMISSION EARLY IN ULCERATIVE COLITIS CLINICAL TRIALS USING COMPUTER VISION ANALYSIS OF ENDOSCOPIC VIDEO
Gastroenterology·2023· 1 citedOpen Access
353 AUTOMATED DIGITAL ULCER QUANTITATION IN COLONOSCOPY IS BETTER ASSOCIATED WITH CLINICAL REMISSION THAN CONVENTIONAL ENDOSCOPIC SCORING IN CROHN'S DISEASE
Gastroenterology·2023
Human β-defensin 2 ameliorates acute GVHD by limiting ileal neutrophil infiltration and restraining T cell receptor signaling
Science Translational Medicine·2022· 21 cited
Gut microbiota bacterial strain richness is species specific and limits therapeutic engraftment
2022· 2 citedOpen Access
Biopsy and blood-based molecular biomarker of inflammation in IBD
Gut·2022· 104 citedOpen Access
Long-term results of teduglutide treatment for chronic intestinal failure – Insights from a national, multi-centric patient home-care service program
Clinical Nutrition ESPEN·2022· 18 cited
S230: HUMAN ΒETA-DEFENSIN 2 TREATMENT MODULATES THE INTESTINAL MICROBIOME AND THE ALLOGENEIC T CELL RESPONSE TO LIMIT ACUTE GRAFT-VERSUS-HOST DISEASE
HemaSphere·2022Open Access
796: COMPUTER VISION MEASUREMENT OF DISEASE SEVERITY DISTRIBUTION OUTPERFORMS TRADITIONAL ENDOSCOPIC SCORING FOR DETECTING THERAPEUTIC RESPONSE IN A CLINICAL TRIAL OF USTEKINUMAB FOR ULCERATIVE COLITIS
Gastroenterology·2022· 1 cited
HBD-2 mutations are associated with childhood asthma and prophylactic hBD-2 application prevents asthma in mice
2021
603 IBD-ASSOCIATED DYSBIOSIS IN UNAFFECTED RELATIVES OF IBD PATIENTS EMERGES IN LATE ADOLESCENCE AND INCREASES WITH AGE
Gastroenterology·2021
Sa473 RISK PROFILING OF UNAFFECTED MEMBERS OF FAMILIES WITH A HISTORY OF IBD USING SEROLOGY SCORE, DYSBIOSIS SCORE, POLYGENIC RISK SCORE, AND FECAL CALPROTECTIN
Gastroenterology·2021· 2 cited
Human β-Defensin 2 Mutations Are Associated With Asthma and Atopy in Children and Its Application Prevents Atopic Asthma in a Mouse Model
Frontiers in Immunology·2021· 22 citedOpen Access
Curbing gastrointestinal infections by defensin fragment modifications without harming commensal microbiota
Communications Biology·2021· 8 citedOpen Access
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Frequent Co-authors

Eduard F. Stange(40), Klaus Fellermann(20), Sabine Nuding(11), Charles Bevins(9), Klaus Herrlinger(8), Matthias Schwab(6), Jürgen Harder(5), Bjoern O. Schroeder(5), Julia Beisner(5), Michael Gersemann(5), Miriam Schlee(4), Péter Fritz(4), Maureen J. Koslowski(4), Guoxing Wang(4), Michael Weichenthal(3), Bo Shen(3), Elke Schaeffeler(3), Hiutung Chu(3), Martin Schaller(3), Irmgard Kübler(3)