Jeanne de la Roche

Medizinische Hochschule Hannover — Germany

Neuroscience · Life Sciences

19h-index2.0kcitations49works16.72yr avg
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Research Topics

Neuroscience and Neuropharmacology Research(10), Ion Channels and Receptors(9), Ion channel regulation and function(8), Pain Mechanisms and Treatments(7), Pluripotent Stem Cells Research(7)

Publications49 total

Patient-specific hiPSC-derived cardiomyocytes indicate allelic and contractile imbalance as pathogenic factor in early-stage Hypertrophic Cardiomyopathy
Journal of Molecular and Cellular Cardiology·2024· 2 cited
Blood-generating heart-forming organoids recapitulate co-development of the human haematopoietic system and the embryonic heart
Nature Cell Biology·2024· 29 citedOpen Access
Functional and structural insights into activation of TRPV2 by weak acids
The EMBO Journal·2024· 19 citedOpen Access
Publisher Correction: Human heart-forming organoids recapitulate early heart and foregut development
Nature Biotechnology·2021· 11 citedOpen Access
Human heart-forming organoids recapitulate early heart and foregut development
Nature Biotechnology·2021· 410 citedOpen Access
TRPV2 Modulation by Small Molecules and Lipids
Biophysical Journal·2021Open Access
TRPV2 interaction with small molecules and lipids revealed by cryo-EM
2020· 7 citedOpen Access
Advanced Single-Cell Mapping Reveals that in hESC Cardiomyocytes Contraction Kinetics and Action Potential Are Independent of Myosin Isoform
Stem Cell Reports·2020· 10 citedOpen Access
Hypertrophic Cardiomyopathy: Prolonged Twitch, Calcium Transients and Action Potentials in Human Stem Cell-Derived Cardiomyocytes with β-Myosin Mutation R723G
Biophysical Journal·2020Open Access
Preclinical development of a miR-132 inhibitor for heart failure treatment
Nature Communications·2020· 201 citedOpen Access
Oxidation of methionine residues activates the high-threshold heat-sensitive ion channel TRPV2
Proceedings of the National Academy of Sciences·2019· 82 citedOpen Access
Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture
Stem Cell Reports·2019· 23 citedOpen Access
Generation of a CFTR knock-in reporter cell line (MHHi006-A-1) from a human induced pluripotent stem cell line
Stem Cell Research·2019· 1 citedOpen Access
Comparing human iPSC-cardiomyocytes versus HEK293T cells unveils disease-causing effects of Brugada mutation A735V of NaV1.5 sodium channels
Scientific Reports·2019· 49 citedOpen Access
Continuous WNT Control Enables Advanced hPSC Cardiac Processing and Prognostic Surface Marker Identification in Chemically Defined Suspension Culture
Stem Cell Reports·2019· 103 citedOpen Access
In Human Embryonic Stem Cell-Derived Cardiomyocytes Twitch Kinetics, Action Potential Parameters and MyH-mRNA Fractions Are Independent of the Expressed Myosin Heavy Chain Isoform
Biophysical Journal·2019Open Access
Activation of renal ClC-K chloride channels depends on an intact N terminus of their accessory subunit barttin
Journal of Biological Chemistry·2018· 7 citedOpen Access
TRPA1 and TRPV1 are required for lidocaine-evoked calcium influx and neuropeptide release but not cytotoxicity in mouse sensory neurons
PLoS ONE·2017· 26 citedOpen Access
Reactive metabolites of acetaminophen activate and sensitize the capsaicin receptor TRPV1
Scientific Reports·2017· 36 citedOpen Access
EBIO Does Not Induce Cardiomyogenesis in Human Pluripotent Stem Cells but Modulates Cardiac Subtype Enrichment by Lineage-Selective Survival
Stem Cell Reports·2017· 17 citedOpen Access
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Frequent Co-authors

Andreas Leffler(16), Robert Zweigerdt(11), Martin Fischer(11), Jörg Ahrens(10), Nilufar Foadi(10), Ulrich Martin(9), Annika Franke(8), Stefan Thiemann(8), M. Leuwer(8), Gertrud Haeseler(8), Mirjam Eberhardt(7), Natalie Weber(7), Theresia Kraft(7), Kristin Schwanke(7), Henning Kempf(6), Peter W. Reeh(5), Klaus Krampfl(5), Florian Wegner(5), Vanessa Buchholz(5), Santoshi Biswanath(4)