Ricardo Gallardo‐Macias

University of Minnesota — United States

Medicine · Health Sciences

12h-index721citations24works1.42yr avg
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Research Topics

HIV/AIDS drug development and treatment(8), HIV Research and Treatment(6), Cell Adhesion Molecules Research(4), Tuberculosis Research and Epidemiology(3), Antibiotic Resistance in Bacteria(3)

Publications24 total

Therapeutic targeting of endothelial calcium signaling accelerates the resolution of lung injury
Signal Transduction and Targeted Therapy·2025Open Access
M64HCl, a focal adhesion kinase activator, promotes intestinal mucosal healing in rats
BMC Gastroenterology·2025· 2 citedOpen Access
Designing Focal Adhesion Kinase (Fak) Activators to Promote Intestinal Mucosal Healing
SSRN Electronic Journal·2025Open Access
Sustained intestinal epithelial monolayer wound closure after transient application of a FAK-activating small molecule
PLoS ONE·2024· 2 citedOpen Access
Small Molecule Benzothiophene with <i>In Vivo</i> Efficacy in a Mouse Model of Drug-Resistant <i>Enterococcus faecium</i> Infection
Journal of Medicinal Chemistry·2024· 3 citedOpen Access
A novel drug-like water-soluble small molecule Focal Adhesion Kinase (FAK) activator promotes intestinal mucosal healing
Current Research in Pharmacology and Drug Discovery·2022· 8 citedOpen Access
Mycobacterium tuberculosis KasA as a drug target: Structure-based inhibitor design
Frontiers in Cellular and Infection Microbiology·2022· 16 citedOpen Access
EP1075: A NOVEL WATER-SOLUBLE SMALL MOLECULE FAK ACTIVATOR PROMOTES INTESTINAL MUCOSAL HEALING
Gastroenterology·2022
Assessment of carbapenems in a mouse model of Mycobacterium tuberculosis infection
PLoS ONE·2021· 2 citedOpen Access
471 REFINEMENT OF SMALL MOLECULE FOCAL ADHESION KINASE ACTIVATORS TO PROMOTE INTESTINAL MUCOSAL HEALING
Gastroenterology·2021
Discovery of Novel Small-Molecule FAK Activators Promoting Mucosal Healing
ACS Medicinal Chemistry Letters·2021· 12 citedOpen Access
Optimization of N-benzyl-5-nitrofuran-2-carboxamide as an antitubercular agent
Bioorganic & Medicinal Chemistry Letters·2018· 17 cited
Human Microbiome Inspired Antibiotics with Improved β-Lactam Synergy against MDR <i>Staphylococcus aureus</i>
ACS Infectious Diseases·2017· 46 citedOpen Access
Discovery of MRSA active antibiotics using primary sequence from the human microbiome
Nature Chemical Biology·2016· 194 citedOpen Access
Discovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase
Bioorganic & Medicinal Chemistry Letters·2015· 20 citedOpen Access
Picomolar Inhibitors of HIV-1 Reverse Transcriptase: Design and Crystallography of Naphthyl Phenyl Ethers
ACS Medicinal Chemistry Letters·2014· 41 citedOpen Access
Structure‐Based Evaluation of C5 Derivatives in the Catechol Diether Series Targeting<scp>HIV</scp>‐1 Reverse Transcriptase
Chemical Biology & Drug Design·2013· 18 citedOpen Access
Picomolar Inhibitors of HIV Reverse Transcriptase Featuring Bicyclic Replacement of a Cyanovinylphenyl Group
Journal of the American Chemical Society·2013· 124 citedOpen Access
CCDC 903205: Experimental Crystal Structure Determination
The Cambridge Structural Database·2013Open Access
Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency
Bioorganic & Medicinal Chemistry Letters·2012· 16 citedOpen Access
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Frequent Co-authors

Karen S. Anderson(8), William L. Jorgensen(8), Vadim J. Gurvich(8), Mariela Bollini(7), Marc D. Basson(7), Joel S. Freundlich(6), Krasimir A. Spasov(6), Kathleen M. Frey(5), Qinggang Wang(5), Mark Jaskowski(4), Rashmi Gupta(4), Mikhail Y. Golovko(4), Sema Oncel(4), John Chu(2), Xavier Vila‐Farrés(2), Daigo Inoyama(2), Shruthi Satish(2), Steven Park(2), Sean F. Brady(2), Won-Gil Lee(2)