Laichuang Han

Jiangnan University — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index874citations66works4.62yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Enzyme Catalysis and Immobilization(14), Enzyme Production and Characterization(14), Bacterial Genetics and Biotechnology(12), Enzyme Structure and Function(9), Pancreatic function and diabetes(8)

Publications66 total

The open-closed transitions within dynamic conformational changes of enzyme loops
Systems Microbiology and Biomanufacturing·2025· 2 cited
Design of a Programmable and Recyclable Protein Scaffolding Material with Geometrically Precise Enzyme Patterning for Improved Cascade Catalysis
Advanced Functional Materials·2025
pH-adaptive evolution of glutamate decarboxylase enables gamma-aminobutyric acid biosynthesis without pH control
Bioresource Technology·2025· 1 cited
Loop engineering in enzymes from structure to function: Mechanisms, methodologies, and engineering strategies
Biotechnology Advances·2025· 5 cited
MicroDFBEST: A dCas12b-derived dual-function base editor with programmable editing characteristics for microbial genetic engineering
Synthetic and Systems Biotechnology·2025Open Access
Interpretable AI-assisted diagnosis of papillary thyroid cancer cytopathology using graph neural networks and knowledge graphs
Scientific Reports·2025Open Access
Construction and validation of a web-based dynamic predictive model for the risk of postoperative nausea and vomiting in patients undergoing day-case hysteroscopic surgery
Frontiers in Medicine·2025Open Access
Evaluation of urinary metabolites as biomarkers for occupational p-chloronitrobenzene exposure: a pilot study
Scientific Reports·2025Open Access
Modification of Flexible Regions for Enhanced Thermal Stability of Alkaline Amylase
Journal of Agricultural and Food Chemistry·2025· 7 cited
Corrigendum to “Reshaping UDP-binding pocket of bacterial sucrose synthase to improve” [Bioresour. Technol. 427 (2025) 132396]
Bioresource Technology·2025Open Access
Reshaping UDP-binding pocket of bacterial sucrose synthase to improve efficiency of UDP-glucose production
Bioresource Technology·2025· 5 cited
Copper silicate nanoparticle-mediated delivery of astragaloside-IV for osteoarthritis treatment by remodeling the articular cartilage microenvironment
Journal of Controlled Release·2025· 13 cited
A Versatile Protein Scaffold Engineered for the Hierarchical Assembly of Robust and Highly Active Enzymes
Advanced Science·2025· 6 citedOpen Access
Efficient expression of recombinant proteins in <i>Bacillus subtilis</i> using a rewired gene circuit of quorum sensing
Biotechnology Progress·2025· 3 cited
Computational design of coevolutionary residues for improved stability and activity of nitrile hydratase
Biochemical and Biophysical Research Communications·2025· 3 cited
Creation of an orthogonal and universal auto-inducible gene expression platform by reprogramming a two-component signal circuit for efficient production of industrial enzymes
International Journal of Biological Macromolecules·2024· 3 cited
Discovery and characterization of temperature adaptation modules by mining L-glutamate decarboxylase derived from psychrophilic microorganisms
International Journal of Biological Macromolecules·2024· 5 cited
Maltose gradient-induced biosensor-based high-throughput screening for directed evolution of maltogenic amylase from Bacillus stearothermophilus
International Journal of Biological Macromolecules·2024
Engineering region flexibility of cellobiohydrolase Ⅰ for efficient hydrolysis of cellulose based on molecular dynamics simulation
Industrial Crops and Products·2024· 6 cited
Multi-method analysis revealed the mechanism of substrate selectivity in NHase: A gatekeeper residue at the activity center
International Journal of Biological Macromolecules·2024· 4 cited
page 1 of 4Next →

Frequent Co-authors

Zhemin Zhou(43), Zhongmei Liu(17), Wenjing Cui(16), Zhongyi Cheng(16), Li Zhou(11), Junling Guo(11), Feiya Suo(9), Wenjing Cui(9), Wenliang Hao(7), Jun Qiao(7), Chenshuo Song(6), Qiaoqing Chen(5), Jie Luo(4), Łukasz Pepłowski(4), Qiao Lin(4), Zhongyi Cheng(4), Qiong Wang(4), Dong Ma(3), Yuanyuan Xia(3), Jintao Cheng(3)