Noel Lenny

University of Tennessee Health Science Center — United States

Medicine · Health Sciences

19h-index5.5kcitations25works0.02yr avg
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Research Topics

Acute Myeloid Leukemia Research(14), Acute Lymphoblastic Leukemia research(8), Retinoids in leukemia and cellular processes(6), Protein Degradation and Inhibitors(4), Epigenetics and DNA Methylation(3)

Publications25 total

Comparing molecular quantification of herpes simplex virus (HSV) in cerebrospinal fluid (CSF) with quantitative structural and functional disease severity in patients with HSV encephalitis (HSVE): Implications for improved therapeutic approaches
Journal of Clinical Virology·2018· 9 cited
Serology Enhances Molecular Diagnosis of Respiratory Virus Infections Other than Influenza in Children and Adults Hospitalized with Community-Acquired Pneumonia
Journal of Clinical Microbiology·2016· 56 citedOpen Access
Community-Acquired Pneumonia Requiring Hospitalization among U.S. Children
New England Journal of Medicine·2015· 1.8k citedOpen Access
Multi-center evaluation of the adenovirus R-gene US assay for the detection of adenovirus in respiratory samples
Journal of Clinical Virology·2014· 11 cited
Acute Lymphoblastic Leukemia-Associated PAX5 Mutations Induce Aberrant B Cell Development
Blood·2010· 1 cited
Haploinsufficiency of Ebf1 Collaborates with BCR-ABL1 to Decrease the Latency of Acute Lymphoblastic Leukemia.
Blood·2008
Role of RUNX1 in adult hematopoiesis: analysis of RUNX1-IRES-GFP knock-in mice reveals differential lineage expression
Blood·2003· 124 citedOpen Access
Classification of pediatric acute lymphoblastic leukemia by gene expression profiling
Blood·2003· 588 citedOpen Access
Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia
Cancer Cell·2002· 437 citedOpen Access
ETO, a Target of t(8;21) in Acute Leukemia, Makes Distinct Contacts with Multiple Histone Deacetylases and Binds mSin3A through Its Oligomerization Domain
Molecular and Cellular Biology·2001· 339 citedOpen Access
The E2A-HLF Oncoprotein Activates<i>Groucho</i>-Related Genes and Suppresses<i>Runx1</i>
Molecular and Cellular Biology·2001· 39 citedOpen Access
Alterations of the AML1 transcription factor in human leukemia
Seminars in Cell and Developmental Biology·2000· 60 cited
Expression of the AML-1 Oncogene Shortens the G1Phase of the Cell Cycle
Journal of Biological Chemistry·2000· 100 citedOpen Access
Expression of a Knocked-In AML1-ETO Leukemia Gene Inhibits the Establishment of Normal Definitive Hematopoiesis and Directly Generates Dysplastic Hematopoietic Progenitors
Blood·1998· 351 citedOpen Access
Expression of a Knocked-In AML1-ETO Leukemia Gene Inhibits the Establishment of Normal Definitive Hematopoiesis and Directly Generates Dysplastic Hematopoietic Progenitors
Blood·1998· 290 citedOpen Access
The t(8;21) Fusion Product, AML-1–ETO, Associates with C/EBP-α, Inhibits C/EBP-α-Dependent Transcription, and Blocks Granulocytic Differentiation
Molecular and Cellular Biology·1998· 272 citedOpen Access
CBFA2, frequently rearranged in leukemia, is not responsible for a familial leukemia syndrome
Leukemia·1997· 15 cited
Transcriptional regulation during myelopoiesis
Molecular Biology Reports·1997· 76 cited
AML-2 is a potential target for transcriptional regulation by the t(8;21) and t(12;21) fusion proteins in acute leukemia.
PubMed·1996· 113 cited
The t(12;21) Translocation Converts AML-1B from an Activator to a Repressor of Transcription
Molecular and Cellular Biology·1996· 278 citedOpen Access
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Frequent Co-authors

James R. Downing(14), Scott W. Hiebert(10), Anami Patel(5), Shari Meyers(3), Hironori Harada(3), Jennifer J. Westendorf(3), Samuel P. Meyers(3), Seema Jain(2), Derek J. Williams(2), Sandra R. Arnold(2), Krow Ampofo(2), Anna M. Bramley(2), Evan J. Anderson(2), Carlos G. Grijalva(2), Wesley H. Self(2), Yuwei Zhu(2), Weston Hymas(2), James D. Chappell(2), David R. Hillyard(2), Dean D. Erdman(2)