Maria Angela De Stefano

Federico II University Hospital — Italy

Medicine · Health Sciences

12h-index501citations26works1.12yr avg
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Research Topics

Thyroid Cancer Diagnosis and Treatment(13), Thyroid Disorders and Treatments(11), Cancer-related Molecular Pathways(9), Growth Hormone and Insulin-like Growth Factors(5), Hedgehog Signaling Pathway Studies(4)

Publications26 total

Therapeutic p63 isoform switching rescues epidermal defects in AEC syndrome
Molecular Therapy·2025
Type 2 Deiodinase in Cancer-Associated Fibroblasts is Required to Sustain Growth of Poorly and Undifferentiated Thyroid Cancer
Thyroid·2025
Type 2 Deiodinase in Cancer-Associated Fibroblasts is required to sustain growth of poorly and undifferentiated thyroid cancer
2025Open Access
The unique signature of tyrosine kinase inhibitor-induced hypothyroidism
The Lancet Diabetes & Endocrinology·2025· 1 cited
Targeted p63 isoform switch corrects dominant mutations in AEC syndrome without disrupting epidermal homeostasis
2025Open Access
FT3 and FT3/FT4 ratio are decreased and not compensated by levothyroxine treatment in TKI-treated thyroid cancer patients
Endocrine Related Cancer·2025· 2 citedOpen Access
Type 2 Deiodinase Promotes Fatty Adipogenesis in Muscle Fibroadipogenic Progenitors From Adult Male Mice
Endocrinology·2025· 5 citedOpen Access
Did selective kinase inhibitors change the management of patients with radioiodine-refractory thyroid cancer?
European Thyroid Journal·2025· 1 citedOpen Access
D898_E901 <i>RET</i> Deletion Is Oncogenic, Responds to Selpercatinib, and Treatment Resistance Can Arise Via RET-Independent Mechanisms
JCO Precision Oncology·2023· 5 citedOpen Access
Altered Thyroid Feedback Loop in Klinefelter Syndrome: From Infancy Through the Transition to Adulthood
The Journal of Clinical Endocrinology & Metabolism·2023· 11 citedOpen Access
Type 2 deiodinase is expressed in anaplastic thyroid carcinoma and its inhibition causes cell senescence
Endocrine Related Cancer·2023· 9 citedOpen Access
Deiodinases in thyroid tumorigenesis
Endocrine Related Cancer·2023· 16 citedOpen Access
Vandetanib downregulates type 2 deiodinase in fibro/adipogenic progenitors
Endocrine Related Cancer·2023· 8 cited
Type 2 Deiodinase Thr92Ala Polymorphism and Aging Are Associated with a Decreased Pituitary Sensitivity to Thyroid Hormone
Thyroid·2023· 8 cited
Combination of Lenvatinib and Pembrolizumab as Salvage Treatment for Paucicellular Variant of Anaplastic Thyroid Cancer: A Case Report
Current Oncology·2021· 13 citedOpen Access
Thyroid Hormone Action in Muscle Atrophy
Metabolites·2021· 34 citedOpen Access
Deiodinases and Cancer
Endocrinology·2021· 32 citedOpen Access
The NANOG Transcription Factor Induces Type 2 Deiodinase Expression and Regulates the Intracellular Activation of Thyroid Hormone in Keratinocyte Carcinomas
Cancers·2020· 21 citedOpen Access
The Thyroid Hormone Inactivator Enzyme, Type 3 Deiodinase, Is Essential for Coordination of Keratinocyte Growth and Differentiation
Thyroid·2020· 24 cited
Author Correction: Thyroid hormone induces progression and invasiveness of squamous cell carcinomas by promoting a ZEB-1/E-cadherin switch
Nature Communications·2020· 6 citedOpen Access
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Frequent Co-authors

Domenico Salvatore(21), Tommaso Porcelli(18), Cristina Luongo(17), Raffaele Ambrosio(15), Daniela Di Girolamo(11), Monica Dentice(10), Caterina Miro(7), Emery Di Cicco(7), Giuseppina Mancino(7), Martin Schlumberger(7), Annunziata Gaetana Cicatiello(6), Annarita Nappi(6), Serena Sagliocchi(5), Caterina Missero(5), Dario Antonini(4), Luigi Del Vecchio(4), Giancarlo Troncone(4), Maddalena Raia(3), Feliciano Visconte(2), Silvia Varricchio(2)