Della David

Babraham Institute — United Kingdom

Medicine · Health Sciences

19h-index2.8kcitations51works16.02yr avg
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Research Topics

Alzheimer's disease research and treatments(17), Genetics, Aging, and Longevity in Model Organisms(14), Prion Diseases and Protein Misfolding(8), Endoplasmic Reticulum Stress and Disease(5), Genetic Neurodegenerative Diseases(4)

Publications51 total

Small-molecule dissolution of stress granules by redox modulation benefits ALS models
Nature Chemical Biology·2025· 22 citedOpen Access
Improved resilience and proteostasis mediate longevity upon DAF-2 degradation in old age
GeroScience·2024· 10 citedOpen Access
A safety mechanism enables tissue-specific resistance to protein aggregation during aging in C. elegans
PLoS Biology·2023· 12 citedOpen Access
Targeted protein degradation: from small molecules to complex organelles—a Keystone Symposia report
Annals of the New York Academy of Sciences·2022· 8 citedOpen Access
The 2021 FASEB Virtual Catalyst Conference on Extracellular and Organismal Proteostasis in Health and Disease, February 3‐4, 2021
The FASEB Journal·2021· 1 citedOpen Access
Tissue-specific safety mechanism results in opposite protein aggregation patterns during aging
2020· 11 citedOpen Access
Extracellular proteostasis prevents aggregation during pathogenic attack
Nature·2020· 65 cited
Integrative Genomics of Lung Tissue Provides Further Insights into the Genetics Architecture of Lung Function Measures
2020
Faculty Opinions recommendation of Developmental ROS individualizes organismal stress resistance and lifespan.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2020
Small molecule modulation of a redox-sensitive stress granule protein dissolves stress granules with beneficial outcomes for familial amyotrophic lateral sclerosis models
2019· 91 citedOpen Access
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans
eLife·2019· 84 citedOpen Access
Author response: Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in Caenorhabditis elegans
2019· 1 citedOpen Access
Faculty Opinions recommendation of SRCP1 conveys resistance to polyglutamine aggregation.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2018
Intrinsically aggregation-prone proteins form amyloid-like aggregates and contribute to tissue aging in <i>C. elegans</i>
2018Open Access
Methods to Study Changes in Inherent Protein Aggregation with Age in &lt;em&gt;Caenorhabditis elegans&lt;/em&gt;
Journal of Visualized Experiments·2017
Methods to Study Changes in Inherent Protein Aggregation with Age in &lt;em&gt;Caenorhabditis elegans&lt;/em&gt;
Journal of Visualized Experiments·2017· 7 citedOpen Access
Faculty Opinions recommendation of Identification of an RNA Polymerase III Regulator Linked to Disease-Associated Protein Aggregation.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature·2017
More stressed out with age? Check your RNA granule aggregation
Prion·2017· 25 citedOpen Access
Age-Dependent Protein Aggregation Initiates Amyloid-β Aggregation
Frontiers in Aging Neuroscience·2017· 57 citedOpen Access
Discovery and functional prioritization of Parkinson’s disease candidate genes from large-scale whole exome sequencing
Genome biology·2017· 120 citedOpen Access
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Frequent Co-authors

Jürgen Götz(18), Marie C. Lechler(10), Frédéric J. Hoerndli(9), Raimund Jung(8), Lars M. Ittner(8), Chaolie Huang(7), Luis Pennanen(5), Pascal Kurosinski(4), Alessandra Ferrari(4), Gabriele S. Kaminski Schierle(4), Nicole Groh(4), Alma L. Burlingame(3), Susanne Hauptmann(3), Isabel Scherping(3), Anne Eckert(3), A Schild(3), Sara Wagner-Valladolid(3), Amberley D. Stephens(3), Chetan Poudel(3), Tessa Sinnige(3)