Stephen J. Mayclin

Center for Infectious Disease Research — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index501citations40works1.32yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Antibiotic Resistance in Bacteria(7), Biochemical and Molecular Research(7), Enzyme Structure and Function(6), Tuberculosis Research and Epidemiology(4), RNA and protein synthesis mechanisms(4)

Publications40 total

Crystal structure of a short-chain dehydrogenase from <i>Brucella ovis</i> with apo and coenzyme NAD <sup>+</sup> -bound protomer chains
Acta Crystallographica Section F Structural Biology Communications·2025Open Access
Architecture of <i>Pseudomonas aeruginosa</i> glutamyl-tRNA synthetase defines a subfamily of dimeric class Ib aminoacyl-tRNA synthetases
Proceedings of the National Academy of Sciences·2025Open Access
Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens
Communications Biology·2024· 3 citedOpen Access
Structure of <i>Plasmodium vivax</i> <i>N</i>-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy
Acta Crystallographica Section F Structural Biology Communications·2024· 2 citedOpen Access
Structural and functional characterization of FabG4 from <i>Mycolicibacterium smegmatis</i>
Acta Crystallographica Section F Structural Biology Communications·2024· 3 citedOpen Access
Crystal structure and biophysical characterization of IspD from <i>Burkholderia thailandensis</i> and <i>Mycobacterium paratuberculosis</i>
Acta Crystallographica Section F Structural Biology Communications·2024Open Access
Characterization of a family I inorganic pyrophosphatase from <i>Legionella pneumophila</i> Philadelphia 1
Acta Crystallographica Section F Structural Biology Communications·2023· 6 citedOpen Access
Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506
Bioorganic & Medicinal Chemistry Letters·2023· 6 cited
X-ray crystallographic studies of pri-miR-21
Acta Crystallographica Section A Foundations and Advances·2022Open Access
Crystal structures of glutamyl-tRNA synthetase from <i>Elizabethkingia anopheles</i> and <i>E. meningosepticum</i>
Acta Crystallographica Section F Structural Biology Communications·2022· 4 citedOpen Access
Broad-spectrum <i>in vitro</i> activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and <i>Leishmania major</i>
Journal of Antimicrobial Chemotherapy·2022· 11 citedOpen Access
Rational design of a new antibiotic class for drug-resistant infections
Nature·2021· 135 cited
Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1
Scientific Reports·2021· 10 citedOpen Access
Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba
PLoS ONE·2021· 23 citedOpen Access
Structural characterization of a GNAT family acetyltransferase from Elizabethkingia anophelis bound to acetyl-CoA reveals a new dimeric interface
Scientific Reports·2021· 17 citedOpen Access
Identification of P218 as a potent inhibitor of <i>Mycobacterium ulcerans</i> DHFR
RSC Medicinal Chemistry·2020· 8 citedOpen Access
<i>Naegleria fowleri:</i> protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba
2020· 1 citedOpen Access
Identification of P218 as a Potent Inhibitor of Mycobacteria Ulcerans DHFR
2020Open Access
Identification of P218 as a Potent Inhibitor of Mycobacteria Ulcerans DHFR
2020Open Access
Crystal Structure of Pseudomonas aeruginosa Penicillin Binding Protein 3 (PAE-PBP3) bound to ETX0462
2020
page 1 of 2Next →

Frequent Co-authors

Thomas E. Edwards(22), Peter J. Myler(17), Bart L. Staker(13), Jan Abendroth(11), Donald D. Lorimer(11), David M. Dranow(9), P.S. Horanyi(6), Sandhya Subramanian(6), Susan K. Buchanan(5), Thomas F. Lerch(5), P. Sharpe(5), Isabelle Phan(5), Lynn K. Barrett(5), Wesley C. Van Voorhis(5), D. Lorimer(5), Thomas F. Durand-Réville(4), Sharon Polleck(4), Jason C. Rouse(4), Phillip G. Pierce(4), Justin K. Craig(4)