Michelle Scalley‐Kim

Seagen (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

8h-index497citations12works0.02yr avg
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Research Topics

RNA and protein synthesis mechanisms(4), Protein Structure and Dynamics(3), Neuropeptides and Animal Physiology(3), Migraine and Headache Studies(2), Monoclonal and Polyclonal Antibodies Research(2)

Publications12 total

The eptinezumab:CGRP complex structure – the role of conformational changes in binding stabilization
Bioengineered·2021· 7 citedOpen Access
Eptinezumab:CGRP Complex Structure and Characterization of the Ligand Binding Interface (1477)
Neurology·2021
Pharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related Peptide
Journal of Pharmacology and Experimental Therapeutics·2020· 42 citedOpen Access
Pharmacologic Characterization of ALD1910, a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase-Activating Peptide
Journal of Pharmacology and Experimental Therapeutics·2019· 60 citedOpen Access
ALD1613, A Novel Long-Acting Monoclonal Antibody to Control ACTH-Driven Pharmacology
Endocrinology·2016· 32 citedOpen Access
Inhibition of chemotaxis induced with mixtures of chemokines by MAb d5d7.
Figshare·2015Open Access
A Novel Highly Potent Therapeutic Antibody Neutralizes Multiple Human Chemokines and Mimics Viral Immune Modulation
PLoS ONE·2012· 8 citedOpen Access
Coevolution of a Homing Endonuclease and Its Host Target Sequence
Journal of Molecular Biology·2007· 73 citedOpen Access
Characterization of the Folding Energy Landscapes of Computer Generated Proteins Suggests High Folding Free Energy Barriers and Cooperativity may be Consequences of Natural Selection
Journal of Molecular Biology·2004· 90 cited
Low free energy cost of very long loop insertions in proteins
Protein Science·2003· 52 citedOpen Access
A “loop entropy reduction” phage‐display selection for folded amino acid sequences
Protein Science·2001· 24 citedOpen Access
NMR characterization of residual structure in the denatured state of protein L
Journal of Molecular Biology·2000· 109 cited

Frequent Co-authors

David Baker(4), Benjamin Dutzar(3), Ethan W. Ojala(3), Charlie Karasek(3), Jens Billgren(3), Erica Stewart(3), Brian Baker(3), John Latham(3), Dan Allison(3), León F. Garcı́a-Martı́nez(3), Carol J. Raport(3), Jenny Mulligan(2), Pei Fan(2), Vanessa Rubin(2), Sam Marzolf(2), David Jurchen(2), Philippe Minard(2), Katie L. Anderson(2), Bruce W. Hess(2), Ryan L. Kelly(2)