Nadeem Q. Mirza

Doylestown Hospital — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

46h-index7.9kcitations95works1.52yr avg
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Research Topics

Breast Cancer Treatment Studies(35), Breast Lesions and Carcinomas(25), Hematopoietic Stem Cell Transplantation(16), Breast Implant and Reconstruction(14), Alzheimer's disease research and treatments(7)

Publications95 total

348 (PB336): ATRN-119, a Novel Macrocyclic ATR Inhibitor, in Patients with Advanced Solid Malignancies: A Phase 1/2a Trial (ABOYA-119)
European Journal of Cancer·2024· 1 cited
77 (PB065): Safety and Preliminary Efficacy of APR-1051, a WEE1 Inhibitor, in a Phase 1 Study of Patients with Cancer-Associated Gene Alterations (ACESOT-1051)
European Journal of Cancer·2024
Abstract CT196: First-in-human phase 1/2a trial of a macrocyclic ATR inhibitor (ATRN-119) in patients with advanced solid tumors
Cancer Research·2024· 3 cited
Abstract CT195: First-in-human phase 1 study of WEE1 inhibitor APR-1051 in patients with advanced solid tumors harboring cancer-associated gene alterations
Cancer Research·2024· 2 cited
Abstract C034: First in Human phase 1/2a trial of a macrocyclic ATR inhibitor (ATRN-119) in patients with advanced solid tumors
Molecular Cancer Therapeutics·2023
P1241: A NOVEL CEREBLON-BINDING MOLECULAR GLUE, SP-3164, SHOWS PRECLINICAL ACTIVITY IN NON-HODGKIN LYMPHOMAS
HemaSphere·2023Open Access
Abstract 524: SP-3164, a novel ikaros and aiolos molecular glue degrader with preclinical activity in non-Hodgkin lymphomas
Cancer Research·2023· 1 cited
Abstract 6253: SP-3164, a novel molecular glue degrader with activity in preclinical models of multiple myeloma
Cancer Research·2023· 1 cited
SP-3164, a Novel Cereblon-Binding Protein Degrader, Shows Activity in Preclinical Lymphoma Models
Blood·2022· 2 cited
Phase 1 trial of seclidemstat (SP-2577) in patients with relapsed/refractory Ewing sarcoma.
Journal of Clinical Oncology·2021· 19 cited
Preliminary efficacy from an ongoing phase 1 dose escalation study of seclidemstat (SP-2577) in patients (pts) with advanced solid tumors (AST).
Journal of Clinical Oncology·2021· 5 cited
Phase 1 expansion trial of the LSD1 inhibitor seclidemstat (SP-2577) with and without topotecan and cyclophosphamide (TC) in patients (pts) with relapsed or refractory Ewing sarcoma (ES) and select sarcomas.
Journal of Clinical Oncology·2021· 3 cited
Risk of Wernicke’s Encephalopathy in Patients with Myeloproliferative Neoplasm
Blood·2014· 1 cited
Other Primary Malignancies in Breast Cancer Patients Treated with Breast Conserving Surgery and Radiation Therapy
Annals of Surgical Oncology·2012· 28 citedOpen Access
Clinicopathologic characteristics and prognostic factors in 420 metastatic breast cancer patients with central nervous system metastasis
Cancer·2007· 184 cited
Long-term outcomes in patients with mucinous, medullary, tubular, and invasive ductal carcinomas after lumpectomy
The American Journal of Surgery·2007· 86 cited
P2–389: Intravenous pulse cyclophosphamide in Alzheimer's disease: Results of a pilot dose–finding study
Alzheimer s & Dementia·2006· 2 cited
Stability of CSF β-Amyloid<sub>1–42</sub> and Tau Levels by APOE Genotype in Alzheimer Patients
Dementia and Geriatric Cognitive Disorders·2006· 16 cited
Gene therapy with<i>E2F-1</i>up-regulates the protein kinase PKR and inhibits growth of leiomyosarcoma<i>in vivo</i>
Molecular Cancer Therapeutics·2005· 16 cited
Hippocampal atrophy in the healthy is initially linear and independent of age
Neurobiology of Aging·2005· 15 cited
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Frequent Co-authors

Kelly K. Hunt(24), S. Eva Singletary(23), Henry M. Kuerer(22), Merrick I. Ross(20), Barry W. Feig(18), Frederick C. Ames(18), Thomas A. Buchholz(14), Gildy V. Babiera(12), Georges Vlastos(11), Funda Meric(10), Lisa A. Newman(9), Funda Meric‐Bernstam(8), Donna Przepiorka(7), Estella Whimbey(6), Ayşegül A. Şahin(6), Savitri Krishnamurthy(5), Jeri S. Akins(5), Marsha D. McNeese(5), Gabriel N. Hortobágyi(5), Raphael E. Pollock(5)