Charlotte E. Farquhar

Massachusetts Institute of Technology — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index548citations35works1.32yr avg
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Research Topics

Advanced biosensing and bioanalysis techniques(12), RNA Interference and Gene Delivery(10), Cannabis and Cannabinoid Research(8), Chemical Synthesis and Analysis(8), Neurotransmitter Receptor Influence on Behavior(5)

Publications35 total

Site-Directed Modification of mRNA with Functionalized Platinum(IV)–Ammines
JACS Au·2026Open Access
Covalent Peptide-Encoded Libraries Enable Discovery of Inhibitors of Epidermal Growth Factor Receptor (EGFR)
2026Open Access
Diarylureas Containing 5‑Membered Heterocycles as CB1 Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation
UNC Libraries·2025Open Access
Rapid Chemical Synthesis of Neuroprotective Hi1a
The Journal of Organic Chemistry·2025
Affinity selection–mass spectrometry with linearizable macrocyclic peptide libraries
Science Advances·2025· 8 citedOpen Access
Single-Shot Synthesis of Neuroprotective Hi1a by Automated Fast-Flow Peptide Synthesis
2025· 1 cited
Abstract C099: Genetic ancestry specific loss of heterozygosity of essential genes as therapeutic vulnerabilities in cancer
Cancer Epidemiology Biomarkers & Prevention·2024
Functionalization of Pt(IV)–Ammines Enables Site-Directed Covalent Modification of mRNA
2024· 1 citedOpen Access
Linearizable Macrocyclic Peptide Libraries for Affinity Selection-Mass Spectrometry
2024· 2 citedOpen Access
MODL-42. BLOOD-BRAIN TUMOR BARRIER ORGANOID MODEL FOR THERAPEUTIC DELIVERY TO GLIOBLASTOMA
Neuro-Oncology·2023· 1 citedOpen Access
Automated Fast-Flow Synthesis of Chromosome 9 Open Reading Frame 72 Dipeptide Repeat Proteins
Journal of the American Chemical Society·2023· 6 cited
Automated Fast-Flow Synthesis of C9orf72 Dipeptide Repeat Proteins
2023Open Access
In-Cell Penetration Selection–Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery
ACS Chemical Biology·2023· 6 citedOpen Access
A Pt(IV)-conjugated brain penetrant macrocyclic peptide shows pre-clinical efficacy in glioblastoma
Journal of Controlled Release·2022· 26 citedOpen Access
Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity
Proceedings of the National Academy of Sciences·2022· 48 citedOpen Access
Correction to “Palladium-Mediated Incorporation of Carboranes into Small Molecules, Peptides, and Proteins”
Journal of the American Chemical Society·2022
A Tumor-Homing Peptide Platform Enhances Drug Solubility, Improves Blood–Brain Barrier Permeability and Targets Glioblastoma
Cancers·2022· 17 citedOpen Access
Palladium-Mediated Incorporation of Carboranes into Small Molecules, Peptides, and Proteins
Journal of the American Chemical Society·2022· 29 cited
In-cell penetration selection—mass spectrometry produces noncanonical peptides for antisense delivery
2022· 1 citedOpen Access
Cell-Penetrating <scp>d</scp> -Peptides Retain Antisense Morpholino Oligomer Delivery Activity
ACS Bio & Med Chem Au·2022· 11 citedOpen Access
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Frequent Co-authors

Bradley L. Pentelute(25), Andrei Loas(19), Carly K. Schissel(9), Thomas F. Gamage(8), Jenny L. Wiley(8), Brian F. Thomas(7), Nina Hartrampf(6), Jacob Rodriguez(4), Joseph S. Brown(4), Thuy Nguyen(4), Yanan Zhang(4), Sean Lawler(4), Annika B. Malmberg(4), Timothy W. Lefever(3), Chengxi Li(3), Bryan H. Bellaire(3), Genwei Zhang(3), Alexander J. Mijalis(3), David Verhoeven(3), Nadezhda German(3)