Florence A. Westholm

Argonne National Laboratory — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index707citations13works0.02yr avg
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Research Topics

Protein Structure and Dynamics(7), Glycosylation and Glycoproteins Research(4), Alzheimer's disease research and treatments(3), Amyloidosis: Diagnosis, Treatment, Outcomes(3), RNA and protein synthesis mechanisms(2)

Publications13 total

A Molecular Model for Self-Assembly of Amyloid Fibrils: Immunoglobulin Light Chains
Biochemistry·1995· 107 cited
Recombinant immunoglobulin variable domains generated from synthetic genes provide a system for in vitro characterization of light‐chain amyloid proteins
Protein Science·1995· 105 citedOpen Access
Pathogenic potential of human monoclonal immunoglobulin light chains: relationship of in vitro aggregation to in vivo organ deposition.
Proceedings of the National Academy of Sciences·1994· 72 citedOpen Access
Novel arrangement of immunoglobulin variable domains: x-ray crystallographic analysis of the .lambda.-chain dimer Bence-Jones protein Loc
Biochemistry·1985· 54 cited
Comparison of chromatographic characteristics of a series of homologous bence—jones proteins during size-exclusion chromatography by high-performance liquid chromatography and by sephadex
Journal of Chromatography A·1985· 4 cited
Small-angle neutron scattering study of Bence-Jones protein Mcg: comparison of structures in solution and in crystal
Biochemistry·1982· 10 cited
Characterization and preliminary crystallographic data on the VL-related fragment of the human κI Bence Jones protein Wat
Journal of Molecular Biology·1981· 10 cited
Preliminary crystallographic data on the human λIII Bence Jones protein dimer Cle
Journal of Molecular Biology·1981· 3 cited
Self-association of human immunoglobulin kappa I light chains: role of the third hypervariable region.
Proceedings of the National Academy of Sciences·1980· 75 citedOpen Access
Crystallographic data on a complete κ-type human Bence-Jones protein
Journal of Molecular Biology·1978· 3 cited
Interconversion of conformational isomers of light chains in the Mcg immunoglobulins
Biochemistry·1978· 40 cited
Binding of 2,4-dinitrophenyl compounds and other small molecules to a crystalline .lambda.-type Bence-Jones dimer
Biochemistry·1974· 163 cited
Isolation and characterization of concanavalin A polypeptide chains
Biochemistry·1971· 61 cited

Frequent Co-authors

M. Schiffer(11), Fred J. Stevens(9), Alan Solomon(6), Allen B. Edmundson(3), Kathryn R. Ely(3), N. C. Panagiotopoulos(3), Elizabeth A. Myatt(2), Manfred Eulitz(2), Deborah Weiss(2), Charles L. Murphy(2), M. Short(2), R. L. Girling(1), Enrique E. Abola(1), M. D. Fausch(1), H.F. Deutsch(1), Chong‐Hwan Chang(1), Alan Solomon(1), Priscilla Wilkins Stevens(1), Rosemarie Raffen(1), Deborah K. Hanson(1)